Multiplexer for controlling fluid in microfluidics chip and microfluidics chip assembly
A multiplexer for controlling a fluid in a microchannel by controlling pneumatic pressure in the microchannel in a microfluidics chip includes: a first pneumatic channel; and a second pneumatic channel forming a cross point which is in communication with the first pneumatic channel, wherein the cross point is in communication with the microchannel of the microfluidics chip, and predetermined pneumatic pressure is provided to the microchannel by using a combination of providing of the pneumatic pressure to the first and second pneumatic channels, channel closing, or channel opening.
1. A multiplexer for controlling a fluid in a microchannel by controlling pneumatic pressure in the microchannel in a microfluidics chip, the multiplexer comprising:
a first pneumatic channel; and
a second pneumatic channel forming a cross point which is in communication with the first pneumatic channel,
wherein the cross point is in communication with the microchannel of the microfluidics chip, and
wherein a predetermined pneumatic pressure is configured to be provided to the microchannel by a combination of pneumatic pressing, channel closing, or channel opening to the first and second pneumatic channels.
2. The multiplexer of claim 1 , wherein the pneumatic pressure is provided to the microchannel, when the pneumatic pressure is provided to both the first and second pneumatic channels or when the pneumatic pressure is provided to any one side of the first and second pneumatic channels and the other side is closed.
3. The multiplexer of claim 1 , wherein
two or more of M first pneuamtic channels separated from each other are provided,
two or more of N second pneumatic channels separated from each other are provided, each of the second pneumatic channels including branch channels branched to correspond to the number M of first pneumatic channels, and
the branch channel forms the cross point by crossing the first pneumatic channel.
4. The multiplexer of claim 3 , wherein the pneumatic pressure may be controlled to be provided independently to M*N microchannels by using M+N first and second pneumatic channels.
5. The multiplexer of claim 1 , further comprising:
a first lamination plate having the first pneumatic channel and a second lamination plate having the second pneumatic channel,
wherein while the second lamination plate overlaps with the first lamination plate, the second pneumatic channel crosses the first pneumatic channel to form the cross point to be in communication with each other, and
while the microfluidics chip vertically overlaps with the first and second lamination plates, the microchannel is in communication with the cross point.
6. The multiplexer of claim 5 , wherein the first lamination plate, the second lamination plate, and the microfluidics chip are sequentially laminated from the top to the bottom, and
the first pneumatic channel, the second pneumatic channel, and the microchannel are provided to the first lamination plate, the second lamination plate, and the microfluidics chip, respectively in a groove shape and the second pneumatic channel being provided in a hole shape at the cross point.
7. The multiplexer of claim 6 , wherein a first through-hole for providing the pneumatic pressure to the first pneumatic channel and a second through-hole for providing the pneumatic pressure to the second pneumatic channel of the second lamination plate are formed in the first laminate plate.
8. A microfluidics chip assembly for controlling a fluid in a microchannel with pneumatic pressure, the microfluidics chip assembly comprising:
a first lamination plate having a first pneumatic channel; and
a second lamination plate having a second pneumatic channel and a cross point where the second pneumatic channel crosses the first pneumatic channel to form the cross point to be in communication with each other; and
a microfluidics chip including a microchannel which is in communication with the cross point while vertically overlapping with the first and second lamination plates,
wherein a predetermined pneumatic pressure is configured to be provided to the microchannel by a combination of pneumatic pressing, channel closing, or channel opening to the first and second pneumatic channels.
9. The microfluidics chip assembly of claim 8 , wherein two or more of M first pneumatic channels separated from each other are provided,
two or more of N second pneumatic channels separated from each other are provided, each of the second pneumatic channels including branch channels branched to correspond to the number M of first pneumatic channels, and
the branch channel forms the cross point by crossing the first pneumatic channel and the microchannel is in communication with the cross point.
10. The microfluidics chip assembly of claim 8 , wherein the first lamination plate, the second lamination plate, and the microfluidics chip are sequentially laminated from the top to the bottom, and
the first pneumatic channel, the second pneumatic channel, and the microchannel are provided to the first lamination plate, the second lamination plate, and the microfluidics chip, respectively in a groove shape and the second pneumatic channel is provided in a hole shape at the cross point.