Material comprising outer layer having entanglement of hydrophobic polymer host blended with anhydride functionalized hydrophobic polymer co-host and hydrophilic guest
The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction.
1. A material comprising:
(i) an outer layer comprising an entanglement; and
(ii) a hydrophilic outer surface of said outer layer,
wherein said entanglement comprises a physical blend of a hydrophobic polymer host and an anhydride functionalized hydrophobic polymer co-host, and a hydrophilic guest;
wherein said hydrophobic polymer host comprises a polyolefin;
wherein said anhydride functionalized hydrophobic polymer co-host comprises a polyolefin which has been functionalized with anhydride functional groups; and
wherein said hydrophilic guest comprises a salt of a glycosaminoglycan;
said entanglement having been synthesized by: (a) intermingling cloaked hydrophilic guest complexes with said physical blend of said host and said co-host; (b) crosslinking molecules of said guest with said guest; and (c) performing a hydrolysis reaction.
2. The material according to claim 1 , wherein: said co-host is selected from the group consisting of: maleic anhydride-graft-polyethylene, maleic anhydride-graft-polypropylene; and maleic anhydride-graft-polystyrene.
3. The material according to claim 1 , wherein said cloaked hydrophilic guest complexes are selected from the group consisting of silylated guest complexes and acylated guest complexes.
4. The material according to claim 3 , wherein said cloaked hydrophilic guest complexes are silylated guest complexes.
5. The material according to claim 1 , wherein said entanglement is surface treated with glycosaminoglycan.
6. The material according to claim 3 , wherein: said co-host is selected from the group consisting of: maleic anhydride-graft-polyethylene, maleic anhydride-graft-polypropylene; and maleic anhydride-graft-polystyrene.
7. The material according to claim 4 , wherein said entanglement is surface treated with glycosaminoglycan.
8. The material according to claim 2 , wherein: said functionalized polyolefin comprises a polyolefin backbone to which the anhydride functional groups have been grafted; and said entanglement, after performing said hydrolysis reaction, having also been: (a) doped with a host-material crosslinking agent and an antioxidant; (b) surface treated using glycosaminoglycan; and (c) crosslinked, using poly(diisocyanate), to crosslink at least a portion of said guest compound with itself.
9. The material according to claim 8 , molded while at least a portion of said host and said co-host are being crosslinked using said host-material crosslinking agent.
10. The material according to claim 9 , wherein said host-material crosslinking agent is selected from the group consisting of silanes and peroxides.
11. The material according to claim 1 , wherein said hydrophilic outer surface of said outer layer is selected from the group consisting of: a bearing surface adapted for mechanical wear; a flexible barrier surface separating a first and second area; a transparent member surface; an in vivo implant surface; a drag reduction surface; a reaction resin surface; a topical dressing surface; and a dental splint surface.
12. The material according to claim 1 , wherein said polyolefin which has been functionalized with anhydride functional groups comprises a polyolefin backbone into which the anhydride functional groups have been incorporated.
13. The material according to claim 12 , wherein said hydrophilic outer surface of said outer layer is selected from the group consisting of: a bearing surface adapted for mechanical wear; a flexible barrier surface separating a first and second area; a transparent member surface; an in vivo implant surface; a drag reduction surface; a reaction resin surface; a topical dressing surface; and a dental splint surface.
14. A medical device comprising the material according to claim 1 .