Granted Patent
B2
US 10,391,186 · App. 15/420,058 · Granted Aug 27, 2019
Actinium-225 compositions of matter and methods of their use
Inventors:
Eva Rachel Birnbaum (Los Alamos, NM); Jonathan W. Engle (Los Alamos, NM); Francois Meiring Nortier (Los Alamos, NM)
Assignee:
Triad National Security, LLC
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Abstract
The present invention is directed to improved methods for generating compositions comprising actinium-225.
Claims (8)
1. A method of treating cancer in a patient comprising administering to the patient an actinium-225 composition comprising the following quotient of activity quantity ratios:
actinium-226/actinium-225 less than 1;
actinium-227/actinium-225 less than 0.03;
cerium-139/actinium-225 less than 0.3;
cerium-141/actinium-225 less than 30;
cerium-143/actinium-225 less than 1; and
lanthanum-140/actinium-225 less than 1.
2. The method of claim 1 , wherein the cancer is breast cancer, a leukemia, a lymphoma, brain cancer, or bone cancer.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 1, 2018
From: LOS ALAMOS NATIONAL SECURITY, LLC
To: TRIAD NATIONAL SECURITY, LLC
Reel/Frame 047401/0957 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 31, 2017
From: BIRNBAUM, EVA RACHEL; ENGLE, JONATHAN W.; NORTIER, FRANCOIS MEIRING
To: LOS ALAMOS NATIONAL SECURITY, LLC
Reel/Frame 041139/0178 →
Continuity (3)
Provisional Application
61887510
· Oct 7, 2013