IP Library › Granted Patent US 10,287,305
Granted Patent B2
US 10,287,305 · App. 15/421,702 · Granted May 14, 2019

Substituted piperidine compound and use thereof

Inventors: Tatsuhiko Fujimoto (Kanagawa, JP); Kentaro Rikimaru (Kanagawa, JP); Hiromichi Sugimoto (Tokyo, JP); Takahiro Matsumoto (Kanagawa, JP)
Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
C07F7/1804C07D211/24C07D211/56C07D401/06C07D401/12C07D401/14C07D405/06C07D405/12C07D405/14C07D409/06C07D409/12C07D413/06C07D417/06C07D417/14
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,287,305
App. No.
15/421,702
Granted
May 14, 2019
Kind
B2
Abstract

Provided is a substituted piperidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as a prophylactic or therapeutic agent for narcolepsy.

Claims (3)

1. Methyl (2R,3S)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or N-((2R,3S)-1-glycoloyl-2-(((cis-4-(2,3,6-trifluorophenyl)cyclohexyl)oxy)methyl)piperidin-3-yl)methanesulfonamide, or a salt thereof.

2. Methyl (2R,3S)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or a salt thereof.

3. N-((2R,3S)-1-glycoloyl-2-(((cis-4-(2,3,6-trifluorophenyl)cyclohexyl)oxy)methyl)piperidin-3-yl)methanesulfonamide or a salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: FUJIMOTO, TATSUHIKO; RIKIMARU, KENTARO; FUKUDA, KOICHIRO; SUGIMOTO, HIROMICHI; MATSUMOTO, TAKAHIRO; TOKUNAGA, NORIHITO; HIROZANE, MARIKO
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 043904/0655 →
Priority Claims (1)
JP 2016-019834 · Feb 4, 2016 · national
Continuity (1)
Related Publication 20170226137A1 · Aug 10, 2017
Cited By (7)
US 12,281,073 US 12,312,332 US 12,441,710 US 12,448,377 US 12,534,471 US 12,594,269 US 12,637,476