IP Library › Granted Patent US 10,695,342
Granted Patent B2
US 10,695,342 · App. 15/431,572 · Granted Jun 30, 2020

Methods and compositions for preventing opioid abuse

Inventors: Matthew Surman (Albany, NY); John K. Thottathil (Ivanhoe, IL); Kathryn Golden (Clifton Park, NY); Paolo Pasetto (Guilderland, NY); Xiaomin Jin (Slingerland, NY); Xiaowu Jiang (East Greenbush, NY); Fatoumata Camara (Albany, NY)
Assignees: ALBANY MOLECULAR RESEARCH, INC.; 3ST RESEARCH LLC
A61K31/485A61K47/542C07D489/08
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Quick Facts
Patent No.
US 10,695,342
App. No.
15/431,572
Granted
Jun 30, 2020
Kind
B2
Abstract

Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.

Claims (3)

1. An abuse-resistant opioid compound selected from the group consisting of:

2. The abuse-resistant opioid compound of claim 1 having the formula:

3. The abuse-resistant opioid compound of claim 1 having the formula:

Assignments (9)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2025
From: CURIA GLOBAL, INC.
To: CURIA BUFFALO R&D, LLC
Reel/Frame 073096/0462 →
CHANGE OF NAME Recorded May 20, 2025
From: ALBANY MOLECULAR RESEARCH, INC.
To: CURIA GLOBAL, INC.
Reel/Frame 071298/0097 →
ASSIGNMENT OF SECURITY INTEREST IN INTELLECTUAL PROPERTY, RECORDED ON SEPTEMBER 1, 2017, AT REEL/FRAME 043746/0621 Recorded Mar 17, 2025
From: BARCLAYS BANK PLC, AS EXISTING AGENT
To: APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT
Reel/Frame 070531/0279 →
SECURITY INTEREST Recorded Sep 6, 2021
From: CURIA GLOBAL, INC. (FKA ALBANY MOLECULAR RESEARCH, INC.); CURIA MASSACHUSETTS, INC. (FKA AMRI BURLINGTON, INC.); CURIA WISCONSIN, INC. (FKA CEDARBURG PHARMACEUTICALS, INC.); CURIA INDIANA, LLC (FKA AMRI SSCI, LLC); CURIA NEW MEXICO, LLC (FKA OSO BIOPHARMACEUTICALS MANUFACTURING, LLC); CURIA IP HOLDINGS, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 057423/0665 →
RELEASE OF SECURITY INTEREST Recorded Oct 29, 2020
From: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
To: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING, LLC
Reel/Frame 054252/0687 →
FIRST LIEN SECURITY AGREEMENT Recorded Sep 1, 2017
From: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING, LLC-BY ITS SOLE MEMBER: ALO ACQUISITION LLC
To: BARCLAYS BANK, PLC AS COLLATERAL AGENT
Reel/Frame 043746/0621 →
SECOND LIEN SECURITY AGREEMENT Recorded Sep 1, 2017
From: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING LLC-BY ITS SOLE MEMBER:ALO ACQUISITION LLC
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 043746/0657 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2017
From: THOTTATHIL, JOHN K.
To: 3ST RESEARCH LLC
Reel/Frame 042970/0929 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 17, 2017
From: SURMAN, MATTHEW; GOLDEN, KATHRYN; PASETTO, PAOLO; JIN, XIAOMIN; JIANG, XIAOWU; CAMARA, FATOUMATA
To: ALBANY MOLECULAR RESEARCH, INC.
Reel/Frame 041289/0162 →
Continuity (3)
Continuation 15139836 · Apr 27, 2016
Provisional Application 62153157 · Apr 27, 2015
Related Publication 20170157116A1 · Jun 8, 2017