IP Library Granted Patent US 9,924,728
Granted Patent B2
US 9,924,728 · App. 15/438,273 · Granted Mar 27, 2018

Food compositions comprising one or both of recombinant beta-lactoglobulin protein and recombinant alpha-lactalbumin protein

Inventors: Ryan Pandya (South San Francisco, CA); Perumal Gandhi (Santa Clara, CA); Shaowen Ji (Ann Arbor, MI); Derek Beauchamp (Dexter, MI); Louis Hom (San Carlos, CA)
Assignee: Perfect Day, Inc.
A23C11/08A23C9/123A23C9/1315A23C19/055A23J3/10C07K14/00C07K14/4732
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Quick Facts
Patent No.
US 9,924,728
App. No.
15/438,273
Granted
Mar 27, 2018
Kind
B2
Abstract

Disclosed herein are methods and compositions including casein, and methods for making these compositions.

Claims (39)

1. A food composition comprising:

(i) a recombinant β-lactoglobulin protein and a recombinant α-lactalbumin protein, wherein one or both of the recombinant β-lactoglobulin protein and the recombinant α-lactalbumin protein comprises a sequence that is at least 90% identical to the bovine protein amino acid sequence and has been produced by a fungal cell;

(ii) one or more sweetening agents;

(iii) ash; and

(iv) optionally, one or more lipids,

wherein:

the food composition has one or more characteristics of a dairy food product selected from the group consisting of: taste, aroma, appearance, handling, mouthfeel, density, structure, texture, elasticity, springiness, coagulation, binding, leavening, aeration, foaming, creaminess, and emulsification; and

the food composition does not comprise any other milk proteins than those in (i).

2. The food composition of claim 1 , wherein

the recombinant β-lactoglobulin protein comprises a sequence that is at least 90% identical to the bovine protein amino acid sequence and has been produced by a fungal cell; and

the recombinant α-lactalbumin protein comprises a sequence that is at least 90% identical to the bovine protein amino acid sequence and has been produced by a fungal cell.

3. The food composition of claim 1 , wherein the fungal cell is selected from the group consisting of: a strain of Aspergillus nidulans , a strain of Aspergillus niger , a strain of Aspergillus oryzae , a strain of Candida albicans , a strain of Trichoderma reesei , a strain of Chrysosporium lucknowense , a strain of Fusarium gramineum , a strain of Fusarium venenatum , a strain of Physcomitrella patens , and a strain of Neurospora crassa.

4. The food composition of claim 1 , wherein one or both of the recombinant β-lactoglobulin protein and the recombinant α-lactalbumin protein has been secreted by a fungal cell.

5. The food composition of claim 1 , wherein the food composition does not include an animal-derived compound.

6. The food composition of claim 1 , wherein the food composition does not include any compound isolated from a milk produced by a mammal.

7. The food composition of claim 1 , wherein the food composition does not include at least one compound otherwise present in a mammal-produced milk.

8. The food composition of claim 1 , wherein the food composition comprises a plurality of micelles.

9. The food composition of claim 8 , wherein the plurality of micelles comprises one or both of the recombinant β-lactoglobulin protein and the recombinant α-lactalbumin protein.

10. The food composition of claim 1 , wherein the food composition comprises one or more lipids selected from the group consisting of: plant-derived oils, plant-derived monoglycerides, plant-derived diglycerides, plant-derived triglycerides, plant-derived free fatty acids, and plant-derived phospholipids.

11. The food composition of claim 1 , wherein the one or more sweetening agents are saccharides selected from the group consisting of: glucose, mannose, maltose, fructose, galactose, lactose, sucrose, monatin, and tagatose.

12. The food composition of claim 1 , wherein the one or more sweetening agents are artificial sweeteners selected from the group consisting of: stevia , aspartame, cyclamate, saccharin, sucralose, mogrosides, brazzein, curculin, erythritol, glycyrrhizin, inulin, isomalt, lacititol, mabinlin, malititol, mannitol, miraculin, monatin, monelin, osladin, pentadin, sorbitol, thaumatin, xylitol, acesulfame potassium, advantame, alitame, aspartame-acesulfame, sodium cyclamate, dulcin, glucin, neohesperidin dihydrochalcone, neotame, and P-4000.

13. The food composition of claim 1 , wherein the ash comprises one or more of: calcium, phosphorous, phosphate, potassium, sodium, citrate, sulfate, carbonate, chloride, magnesium, iron, copper, zinc, manganese, selenium, iodine, retinol, carotene, vitamins, vitamin D, vitamin E, vitamin B12, thiamin, and riboflavin, or a salt(s) thereof.

14. The food composition of claim 1 , wherein the ash has a final concentration in the food composition of about 5% w/w to about 7% w/w.

15. The food composition of claim 1 , wherein the food composition is selected from the group consisting of: a yogurt, a cheese, a milk, a butter, a caseinate, a cream, an infant formula, an ice cream, a frozen custard, a cottage cheese, a cream cheese, a crème fraiche, and a curd.

16. The food composition of claim 1 , wherein the food composition is a powder composition.

17. The food composition of claim 15 , wherein the food composition is a yogurt.

18. The food composition of claim 15 , wherein the food composition is a butter.

19. The food composition of claim 15 , wherein the food composition is a caseinate.

20. The food composition of claim 15 , wherein the food composition is a cream.

21. The food composition of claim 15 , wherein the food composition is an ice cream.

22. The food composition of claim 15 , wherein the food composition is a frozen custard.

23. The food composition of claim 15 , wherein the food composition is a cottage cheese.

24. The food composition of claim 15 , wherein the food composition is a cream cheese.

25. The food composition of claim 15 , wherein the food composition is a crème fraiche.

26. The food composition of claim 15 , wherein the food composition is a curd.

27. The food composition of claim 7 , wherein the food composition does not include lactose.

28. The food composition of claim 7 , wherein the food composition does not include a hormone.

29. The food composition of claim 15 , wherein the food composition is a milk.

30. The food composition of claim 15 , wherein the food composition is a cheese.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2017
From: PANDYA, RYAN; GANDHI, PERUMAL; JI, SHAOWEN; BEAUCHAMP, DEREK; HOM, LOUIS
To: PERFECT DAY, INC.
Reel/Frame 041829/0142 →
Continuity (3)
Continuation PCTUS2015046428 · Aug 21, 2015
Provisional Application 62040393 · Aug 21, 2014
Related Publication 20170164632A1 · Jun 15, 2017