IP Library › Patent Application 15471128
Patent Application
App. No. 15/471,128

NUCLEOSIDE PHOSPHORAMIDATES

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Quick Facts
Patent No.
US None
App. No.
15/471,128
Abstract

Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.

Claims (3)

1 .- 81 . (canceled)

82 . A compound of formula:

wherein Z is —C(O)(CH 2 ) 2 C(O)CH 3, —Si(CH 3 ) 2 t Bu or —Si(i—Pr) 2 -O—Si(i—Pr) 2 -OH.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2017
From: ROSS, BRUCE; SOFIA, MICHAEL JOSEPH; PAMULAPATI, GANAPATI REDDY; RACHAKONDA, SUGUNA; ZHANG, HAI-REN; CHUN, BYOUNG-KWON; WANG, PEIYUAN
To: PHARMASSET, INC.
Reel/Frame 043739/0653 →
CHANGE OF NAME Recorded Sep 29, 2017
From: PHARMASSET, INC.
To: GILEAD PHARMASSET LLC
Reel/Frame 044068/0875 →