IP Library Patent Application 15471783
Patent Application
App. No. 15/471,783

Method of Inhibiting Mucin Secretion

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Patent No.
US None
App. No.
15/471,783
Abstract

A method of inhibiting mucus secretion in an individual that includes administering an effective amount of a composition which comprises guaifenesin.

Claims (32)

1 . A method of inhibiting mucus secretion in an individual comprising administering an effective amount of a composition comprising guaifenesin.

2 . The method as claimed in claim 1 , wherein the composition comprises from approximately 600 mg-1200 mg of guaifenesin.

3 . The method as claimed in claim 2 , wherein the composition comprises approximately 600 mg of guaifenesin.

4 . The method as claimed in claim 2 , wherein the composition comprises approximately 1200 mg of guaifenesin.

5 . The method as claimed in claim 1 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a tablet.

6 . The method as claimed in claim 1 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a powder.

7 . The method as claimed in claim 1 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a capsule.

8 . The method as claimed in claim 1 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a liquid.

9 . The method as claimed in claim 1 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a liquigel.

10 . The method as claimed in claim 1 , wherein the mucus secretion is produced in the upper respiratory tract of an individual.

11 . The method as claimed in claim 1 , wherein the composition further comprises one or more active agents.

12 . The method as claimed in claim 11 , wherein the one or more active agents are selected from the group consisting of an antitussive, a decongestant, and an antihistamine.

13 . The method as claimed in claim 12 , wherein the antitussive comprises dextromethorphan hydrobromide.

14 . The method as claimed in claim 12 , wherein the decongestant is selected from the group consisting of phenylephrine hydrochloride, pseudoephedrine hydrochloride and ephedrine.

15 . The method as claimed in claim 12 , wherein the antihistamine is selected from the group consisting of chlorpheniramine maleate, brompheniramine maleate, phenindamine tartrate, pyrilamine maleate, doxylamine succinate, phenyltoloxamine citrate, diphenhydramine hydrochloride, promethazine, clemastine fumerate, and fexofenadine, or a combination thereof.

16 . The method as claimed in claim 1 , wherein the composition comprises an immediate release portion and a sustained release portion, such that the inhibition of mucus secretion is therapeutically achieved for a period of approximately 12 hours.

17 . A method of treating an individual having a disease or condition characterized by increased mucin secretion with an effective amount of a composition comprising guaifenesin.

18 . The method as claimed in claim 17 , wherein the composition comprises from approximately 600 mg-1200 mg of guaifenesin.

19 . The method as claimed in claim 18 , wherein the composition comprises approximately 600 mg of guaifenesin.

20 . The method as claimed in claim 18 , wherein the composition comprises approximately 1200 mg of guaifenesin.

21 . The method as claimed in claim 17 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a tablet.

22 . The method as claimed in claim 17 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a powder.

23 . The method as claimed in claim 17 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a capsule.

24 . The method as claimed in claim 17 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a liquid.

25 . The method as claimed in claim 17 , wherein administering an effective amount of a composition comprising guaifenesin comprises administering the composition as a liquigel.

26 . The method as claimed in claim 17 , wherein the mucus secretion is produced in the upper respiratory tract of an individual.

27 . The method as claimed in claim 17 , wherein the composition further comprises one or more active agents.

28 . The method as claimed in claim 27 , wherein the one or more active agents are selected from the group consisting of an antitussive, a decongestant, and an antihistamine.

29 . The method as claimed in claim 28 , wherein the antitussive comprises dextromethorphan hydrobromide.

30 . The method as claimed in claim 28 , wherein the decongestant is selected from the group consisting of phenylephrine hydrochloride, pseudoephedrine hydrochloride and ephedrine.

31 . The method as claimed in claim 28 , wherein the antihistamine is selected from the group consisting of chlorpheniramine maleate, brompheniramine maleate, phenindamine tartrate, pyrilamine maleate, doxylamine succinate, phenyltoloxamine citrate, diphenhydramine hydrochloride, promethazine, clemastine fumerate, and fexofenadine, or a combination thereof.

32 . The method as claimed in claim 17 , wherein the composition comprises an immediate release portion and a sustained release portion, such that the inhibition of mucus secretion is therapeutically achieved for a period of approximately 12 hours.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2019
From: RECKITT BENCKISER LLC
To: RB HEALTH (US) LLC
Reel/Frame 049451/0056 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2017
From: ALBRECHT, HELMUT; KIM, K. CHUL; RUBIN, BRUCE; SEAGRAVE, JEANCLARE; SOLOMON, GAIL
To: RECKITT BENCKISER INC
Reel/Frame 041769/0836 →
CERTIFICATE OF CONVERSION Recorded Mar 28, 2017
From: RECKITT BENCKISER INC
To: RECKITT BENCKISER LLC
Reel/Frame 042107/0954 →