IP Library Granted Patent US 10,139,459
Granted Patent B2
US 10,139,459 · App. 15/474,510 · Granted Nov 27, 2018

Passive MRI-guided tracking of metallic objects using artifact-reduced imaging with selective excitation

Inventors: Hans Weber (Menlo Park, CA); Brian A. Hargreaves (Menlo Park, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
G01R33/287G01R33/4833G01R33/5611
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Quick Facts
Patent No.
US 10,139,459
App. No.
15/474,510
Granted
Nov 27, 2018
Kind
B2
Abstract

A method using 2D multi-spectral imaging (2DMSI) for MRI imaging of a metallic object (such as a biopsy needle) and region surrounding the metallic object within an imaging field of view of an MRI apparatus includes segmenting the imaging field-of-view into spatial-spectral bins, where the segmenting is based on off-resonance frequency induced by the metallic object and slice location; selectively exciting each frequency bin of the spatial-spectral bins by inverting a slice selection gradient between excitation and refocusing pulses; performing repeated acquisition with different radiofrequency modulations to produce acquired images of adjacent bins; composing a 2DMSI image by root-sum-of-squares combination of the acquired images of adjacent bins; and highlighting in the 2DMSI image an area of furthest off-resonance bins based on 2DMSI off-resonance information by thresholding image intensity in frequency bins, thereby indicating a contour of the metallic object.

Claims (13)

1. A method using 2D multi-spectral imaging (2DMSI) for MRI imaging of a metallic object and region surrounding the metallic object within an imaging field of view of an MRI apparatus, the method comprising:

segmenting the imaging field-of-view into spatial-spectral bins, where the segmenting is based on off-resonance frequency induced by the metallic object and the slice location;

selectively exciting each spatial-spectral bin by inverting a slice selection gradient between excitation and refocusing pulses;

performing repeated acquisition with different radiofrequency modulations to produce acquired images of adjacent frequency bins;

composing a 2DMSI image by combination of the acquired images of adjacent bins;

highlighting in the 2DMSI image an area of off-resonance bins based on 2DMSI off-resonance information by thresholding image intensity in frequency bins, thereby indicating a contour of the metallic object.

2. The method of claim 1 wherein highlighting in the 2DMSI image comprises color-coding the image area based on the sign of the off-resonance frequency of the bin.

3. The method of claim 1 wherein the method is continuously repeated to acquire a series of 2DMSI images.

4. The method of claim 1 further comprising changing a contrast of the 2DMSI image by selectively inverting each bin with an inversion pulse.

5. The method of claim 1 wherein only a subset of bins is acquired.

6. The method of claim 5 wherein the subset of bins comprises the on-resonant bin and the furthest off-resonance bins.

7. The method of claim 5 wherein the subset of bins comprises only the furthest off-resonance bins and where the information is used to highlight the corresponding image areas in a conventionally acquired MRI image.

8. The method of claim 1 wherein parallel imaging is used to accelerate the data acquisition.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 17, 2017
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 042482/0374 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2017
From: WEBER, HANS; HARGREAVES, BRIAN A.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 041889/0972 →
Continuity (1)
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