IP Library Granted Patent US 10,285,795
Granted Patent B2
US 10,285,795 · App. 15/487,585 · Granted May 14, 2019

Method and apparatus for creating a reconstructive graft

Inventor: Barry Markman (Las Vegas, NV)
Assignee: Markman Biologics Corporation
A61F2/0077A61F2/0063A61L27/54A61F2002/0068A61F2002/0081A61F2240/002A61F2240/005A61F2250/0026A61F2250/0048A61F2250/0051A61F2250/0067
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Quick Facts
Patent No.
US 10,285,795
App. No.
15/487,585
Granted
May 14, 2019
Kind
B2
Abstract

A method and apparatus is provided for creating an internal reconstruction tissue graft. Templates may be used to create a multitude of patterns in a variety of tissue reconstruction grafts. An apparatus may be used to create an internal tissue graft for reconstruction through either compression and/or removal of segments. An apparatus may be used, through either compression and or removal of segments of a preformed template made of synthetics and or metal that mirrors a template that can be used as an internal tissue graft for reconstruction. In a method, such as using software analysis and an apparatus, the physical properties of the tissue graft and its pre- and post-operative properties and appearance may be measured.

Claims (14)

1. A reconstructive tissue graft for placement at an anatomical site of a human, said reconstructive tissue graft prepared by a process comprising the steps of:

modifying an exterior surface of a tissue graft obtained from a site other than said anatomical site to include one or more designed surface features, said designed surface features comprising one or more openings; and

associating at least one medicant, secondary tissue or other material with one or more of said designed surface features comprising at least partially filling said one or more openings.

2. The reconstructive tissue graft in accordance with claim 1 wherein said tissue graft comprises human tissue.

3. The reconstructive tissue graft in accordance with claim 2 wherein said human tissue comprises soft, non-bone, tissue.

4. The reconstructive tissue graft in accordance with claim 1 wherein said at least one medicant comprises one or more of an antibiotic, a hormone, a growth factor and a chemotherapeutic agent.

5. The reconstructive tissue graft in accordance with claim 1 wherein said other material comprises one or more of acellular human tissue, non-human tissue, stem cells and at least one synthetic material.

6. The reconstructive tissue graft in accordance with claim 1 wherein said one or more designed surface features comprise one or more voids, pockets, sleeves, channels, depressions, projections and folds at said exterior surface of said tissue graft.

7. The reconstructive tissue graft in accordance with claim 1 wherein said step of modifying comprises removing material from one or more areas of said exterior surface of said tissue graft.

8. The reconstructive tissue graft in accordance with claim 7 wherein said step of removing comprises or more of cutting and punching.

9. A reconstructive tissue graft for placement at an anatomical site of a human, said reconstructive tissue graft prepared by a process comprising the steps of:

modifying an exterior surface of a tissue graft having a first surface area, said tissue graft obtained from a site other than said anatomical site to include one or more designed surface features, said designed surface features causing said tissue graft to have a second increased surface area which is greater than said first surface area, one or more of said designed surface features comprising pockets created by punching material from said tissue graft; and

associating at least one medicant, secondary tissue or other material with at least a portion of said exterior surface of said tissue graft which includes one or more of said designed surface features.

10. The reconstructive tissue graft in accordance with claim 9 wherein said one or more designed surface feature comprise one or more pockets extending into said exterior surface of said tissue graft.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF APPLICANT PREVIOUSLY RECORDED ON REEL 67051 FRAME 308. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 16, 2025
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX CORP
Reel/Frame 072050/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2024
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX
Reel/Frame 067051/0308 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2024
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 067032/0745 →
SECURITY INTEREST Recorded Aug 28, 2020
From: MARKMAN BIOLOGICS CORPORATION
To: MARKMAN, BARRY
Reel/Frame 053627/0532 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2019
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 048466/0528 →
Continuity (5)
Continuation 14678188 · Apr 3, 2015
Continuation In Part 13687082 · Nov 28, 2012
Continuation 13101022 · May 4, 2011
Provisional Application 61331805 · May 5, 2010
Related Publication 20170216008A1 · Aug 3, 2017