IP Library Granted Patent US 9,987,491
Granted Patent B2
US 9,987,491 · App. 15/499,511 · Granted Jun 5, 2018

Stimulation of a hypoglossal nerve for controlling the position of a patient's tongue

Inventors: Marcelo G. Lima (San Diego, CA); Paul M. Meadows (Glendale, CA); Jasper Benke (San Diego, CA)
Assignee: IMTHERA MEDICAL, INC.
A61N1/3611A61N1/0551A61N1/36167A61N1/3787A61N1/0556
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Quick Facts
Patent No.
US 9,987,491
App. No.
15/499,511
Granted
Jun 5, 2018
Kind
B2
Abstract

A method for controlling a position of a patient's tongue includes attaching at least one electrode to the patient's hypoglossal nerve, applying an electric signal through the electrode to the hypoglossal nerve to stimulate at least one muscle of the tongue at least until the number of obstructive sleep apnea occurrences are reduced from an initial level to a treatment level, and reducing the application of the electric signal while the number of obstructive sleep apnea occurrences remain generally at or below the treatment level.

Claims (12)

1. A method for controlling a position of a patient's tongue, the method comprising:

applying an electric signal through at least one electrode to a hypoglossal nerve to stimulate at least one muscle of the patient's tongue at least until a number of obstructive sleep apnea occurrences is reduced from an initial level to a treatment level; and

ceasing the application of the electric signal for a period of time while the number of obstructive sleep apnea occurrences during the period of time remains generally at or below the treatment level.

2. The method of claim 1 , wherein applying and ceasing the application of the electric signal is repeated a plurality of times, the application of the the electric signal having an Intra-Session Periodicity.

3. The method of claim 1 , wherein applying and ceasing the application of the electric signal is repeated a plurality of times, the application of the the electric signal having an Inter-Session Periodicity.

4. The method of claim 1 , wherein the application of the electric signal includes applying an initial electric signal that gradually increases over time and then levels off.

5. The method of claim 1 , wherein the electric signal is applied to at least one targeted motor efferent of the hypoglossal nerve.

6. The method of claim 1 , wherein the electric signal is applied when the patient is asleep.

7. The method of claim 1 , wherein the electric signal is applied when the patient is awake.

8. A system for controlling a position of a patient's tongue, the system comprising: at least one electrode configured to attach to the patient's hypoglossal nerve; and an implantable pulse generator programmed to perform a method according to claim 1 .

9. A non-transitory computer readable storage medium having stored thereon computer-executable instructions which, when executed by a processor, perform a method according to claim 1 .

10. The method of claim 1 , wherein ceasing the application of the electric signal is conducted independent of feedback from or action by the patient.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Sep 20, 2021
From: ACF FINCO I LP
To: IMTHERA MEDICAL, INC.
Reel/Frame 057535/0850 →
SECURITY INTEREST Recorded Aug 16, 2021
From: IMTHERA MEDICAL, INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 057188/0115 →
RELEASE OF SECURITY INTEREST Recorded Aug 16, 2021
From: ARES CAPITAL CORPORATION, AS AGENT FOR THE LENDERS
To: IMTHERA MEDICAL, INC.
Reel/Frame 057188/0573 →
PATENT SECURITY AGREEMENT Recorded Dec 30, 2020
From: IMTHERA MEDICAL, INC.
To: ACF FINCO I LP, AS COLLATERAL AGENT
Reel/Frame 054881/0683 →
PATENT SECURITY AGREEMENT Recorded Jun 17, 2020
From: IMTHERA MEDICAL, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 052963/0651 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 30, 2017
From: LIMA, MARCELO G.; MEADOWS, PAUL M.; BENKE, JASPER
To: IMTHERA MEDICAL, INC.
Reel/Frame 042188/0125 →
Continuity (4)
Continuation 15058722 · Mar 2, 2016
Continuation 14400733
Provisional Application 61647122 · May 15, 2012
Related Publication 20170224988A1 · Aug 10, 2017