Porous devices, kits, and methods for debridement
Porous devices are provided that include a particle-containing fibrous porous matrix and a fluid absorbed in the particle-containing porous fibrous nonwoven matrix. The particle-containing fibrous porous matrix includes a porous fibrous nonwoven matrix containing first polyolefin fibers, second polyolefin fibers including poly(ethylene), and fiberglass fibers; and microorganism-binding particles. The microorganism-binding particles are enmeshed in said porous fibrous nonwoven matrix. Methods of debridement are provided including providing a porous device including a particle-containing fibrous porous matrix and wiping a wound or an area of skin with the device; and providing a porous device including a porous fibrous nonwoven matrix and wiping a wound with the device. Further, kits are provided including a sterile package containing at least one porous device, and typically also instructions for debridement.
1. A device comprising:
(a) a particle-containing porous fibrous nonwoven matrix comprising:
(i) a porous fibrous nonwoven matrix in the form of a layer of interlaid fibers comprising first polyolefin fibers, second polyolefin fibers comprising polyethylene, and fiberglass fibers; and
(ii) a plurality of microorganism-binding particles; wherein the particles are enmeshed in the porous fibrous nonwoven matrix; and
(b) a fluid absorbed in the particle-containing porous fibrous nonwoven matrix.
2. The device of claim 1 wherein the fluid is present in an amount of at least 0.25 grams per gram of the particle-containing porous fibrous nonwoven matrix.
3. The device of claim 1 wherein the microorganism-binding particles comprise particles selected from the group consisting of amorphous metal silicates, guanidine-functionalized metal silicates, diatomaceous earth, surface-modified diatomaceous earth, gamma-FeO(OH), metal carbonates, metal phosphates, silica, and combinations thereof.
4. The device of claim 1 wherein the second polyolefin fibers comprise bi-component polymeric fibers comprising a core-sheath structure, a side-by-side structure, an islands-in-the-sea structure, or a segmented-pie structure.
5. The device of claim 1 wherein the device further comprises a substrate laminated to a major surface of the particle-containing porous fibrous nonwoven matrix.
6. The device of claim 1 wherein the fluid comprises water, a buffer solution, a cleansing solution, an analgesic solution, or an antimicrobial solution.
7. The device of claim 1 wherein the device is sterile.
8. A kit comprising (a) a sterile package and (b) at least one device of claim 1 disposed in the sterile package.
9. A method of debridement comprising:
(a) providing a device comprising a particle-containing porous fibrous nonwoven matrix comprising:
(i) a porous fibrous nonwoven matrix in the form of a layer of interlaid fibers comprising first polyolefin fibers, second polyolefin fibers comprising polyethylene, and fiberglass fibers; and
(ii) a plurality of microorganism-binding particles; wherein the particles are enmeshed in the porous fibrous nonwoven matrix; and
(b) wiping a wound or an area of skin with the device.
10. The method of claim 9 wherein the method further comprises adding a fluid to the particle-containing porous fibrous nonwoven matrix before the wiping.
11. The method of claim 9 wherein the device further comprises a fluid absorbed in the particle-containing porous fibrous nonwoven matrix.
12. The method of claim 10 wherein the fluid comprises water, a buffer solution, a cleansing solution, an analgesic solution, or an antimicrobial solution.
13. The method of claim 9 wherein the wiping provides at least a 2.0 log reduction in an amount of microorganisms on the wound or the area of skin.
14. The method of claim 9 wherein the microorganism-binding particles comprise particles comprise particles of amorphous metal silicates, guanidine-functionalized metal silicates, diatomaceous earth, surface-modified diatomaceous earth, gamma-FeO(OH), or a combination thereof.