IP Library › Granted Patent US 10,529,454
Granted Patent B2
US 10,529,454 · App. 15/518,834 · Granted Jan 7, 2020

Human metabolic condition management

Inventor: Bradley E. Kahlbaugh (Bloomington, MN)
G16H50/50A61B5/14532A61B5/7275A61M5/14244A61M5/1723G06F19/3456G06F19/3475G06F19/3481G16H50/30A61M2005/1726
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Quick Facts
Patent No.
US 10,529,454
App. No.
15/518,834
Granted
Jan 7, 2020
Kind
B2
Abstract

Systems and methods for extracting blood glucose patterns and suggesting a behavior may include receiving, at a computing device comprising a processor, temporal data including information regarding glucose readings; identifying, by the computing device, at least one pattern based on metabolite levels extracted from the temporal data the model including variables corresponding to each of the patterns; formulating, by the computing device, a model for predicting a metabolic response; and storing the model on a data storage device. Based on the model, the behavior may be suggested to maintain a blood glucose level within a desired range.

Claims (44)

1. A method comprising:

receiving, at a computing device comprising a processor, temporal data including information regarding metabolite readings;

identifying, by the computing device, at least one pattern based on metabolite levels extracted from the temporal data;

formulating, by the computing device, a model for predicting a metabolite level change, the model including variables corresponding to the at least one identified pattern;

validating the model against a subsample of the temporal data not used to formulate the model;

storing the model on a data storage device;

receiving, at the computing device, a behavior input from a user, the behavior input including an indication of an ingestion of a food item or the administration of a medication;

determining, by the computing device, a metabolite level change based at least in part on the model;

selecting, by the computing device, a recommended behavior;

outputting the recommended behavior to a display associated with the computing device; and

performing the recommended behavior by the user.

2. The method of claim 1 , wherein the information regarding metabolite readings includes glucose readings that include information regarding at least one of a medication taken, a food item ingested, or an activity undertaken.

3. The method of claim 1 , wherein the at least one identified pattern includes an increase in a blood glucose level.

4. The method of claim 3 , wherein the increase in the blood glucose level is due to ingestion of the food item or administering the medication.

5. The method of claim 1 , wherein the at least one identified pattern includes a decrease in a blood glucose level.

6. The method of claim 5 , wherein the decrease in the blood glucose level is due to administering the medication or undertaking an activity.

7. The method of claim 1 , wherein the temporal data includes exercise activities engaged in by the user that result in a change in a blood glucose level.

8. The method of claim 1 , wherein the temporal data includes t metabolite levels recorded over a time interval.

9. The method of claim 1 , wherein the model is formulated according to at least one of a statistical analysis, a Monte Carlo simulation, a single variable regression analysis, and a multivariable regression analysis.

10. The method of claim 1 , wherein receiving the temporal data includes receiving updated temporal data, the method further comprising:

identifying an updated pattern based on metabolite levels extracted from the updated temporal data; and

wherein validating the model includes validating the model against the updated pattern.

11. The method of claim 10 , further comprising formulating a new model when the model does not validate against the updated pattern.

12. The method of claim 11 , wherein the recommended behavior includes two or more coupled metabolic effects.

13. A system comprising:

a display;

a processor in electrical communication with the display; and

a memory that store instructions that, when executed by the processor, cause the processor to perform operations comprising:

receiving temporal data including information regarding metabolite readings,

identifying at least one pattern based on metabolite levels extracted from the temporal data,

formulating a model for predicting a metabolite level change, the model including variables corresponding to the at least one identified pattern,

validating the model against a subsample of the temporal data not used to formulate the model,

storing, to the memory, the model

receiving a behavior input from a user, the behavior input including an indication of an ingestion of a food item or the administration of a medication,

determining a metabolite level change based at least in part on the model,

selecting a recommended behavior,

outputting the recommended behavior to a display associated with the computing device, and

receiving an indication the user accepted the recommendation.

14. The system of claim 13 , wherein the model comprises a sigmoid form.

15. The system of claim 13 , wherein receiving the temporal data includes receiving updated temporal data, and wherein the operations further comprise:

identifying an updated pattern based on metabolite levels extracted from the updated temporal data; and

wherein validating the model includes validating the model against the updated pattern.

16. The system of claim 15 , wherein the operations further comprise formulating a new model when the model does not validate against the updated pattern.

17. The system of claim 13 , wherein the system is one of a blood glucose meter, an infusion pump, and a smartphone.

Continuity (2)
Provisional Application 62065146 · Oct 17, 2014
Related Publication 20170242975A1 · Aug 24, 2017