IP Library › Granted Patent US 11,608,340
Granted Patent B2
US 11,608,340 · App. 15/527,283 · Granted Mar 21, 2023

Nanomaterial compositions, synthesis, and assembly

Inventors: Qian Chen (Barrington, RI); Hongchuan Yu (Mansfield, MA); Yupeng Chen (Mansfield, MA)
Assignee: Rhode Island Hospital
C07D487/04A61K45/06A61K47/542A61K47/545A61K47/6925A61L27/20A61L27/227A61L27/50A61L27/52A61L27/54C07D471/04C07D519/00A61F2/30756A61L2300/252A61L2300/406A61L2300/414A61L2400/12
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Quick Facts
Patent No.
US 11,608,340
App. No.
15/527,283
Granted
Mar 21, 2023
Kind
B2
Abstract

Compositions or an assembly of a series of biomimetic compounds include chemical structures that mimic or structurally resemble a nucleic acid base pair. Complexes of nanotubes and agents are useful to deliver agents into the cells or bodily tissues of individuals for therapeutic and diagnostic purposes. Exemplary compounds include those of Formula (I), (III), (V) or (VII), or of Formula (II), (IV), (VI) or (VIII).

Claims (5)

1. A composition comprising a compound having a structure of

or a pharmaceutically acceptable salt thereof,

wherein the compound self-assembles to form a nanotube.

2. A compound having a structure of

(Compound A), or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2017
From: CHEN, QIAN; YU, HONGCHUAN; CHEN, YUPENG
To: RHODE ISLAND HOSPITAL
Reel/Frame 043257/0097 →
Continuity (2)
Provisional Application 62080685 · Nov 17, 2014
Related Publication 20170362238A1 · Dec 21, 2017
Cited By (1)
US 12,534,468