IP Library Granted Patent US 10,369,174
Granted Patent B2
US 10,369,174 · App. 15/534,068 · Granted Aug 6, 2019

Pharmaceutical composition for preventing or treating metabolic diseases, comprising bacteroides acidifaciens as active ingredient

Inventors: Mi Na Kweon (Seoul, KR); Jin Young Yang (Seoul, KR)
Assignee: GI BIOME
A61K35/74A23L33/135A23L33/30A23L33/40A61K35/66A61K38/1709A61K45/06C12N5/0639A23V2002/00C12N2510/00
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Quick Facts
Patent No.
US 10,369,174
App. No.
15/534,068
Granted
Aug 6, 2019
Kind
B2
Abstract

The present disclosure relates to a composition for preventing or treating metabolic diseases, in which the composition includes Bacteroides acidifaciens as an active ingredient. In addition, the present disclosure relates to a composition for oxidizing fat or inhibiting DPP-4, in which the composition includes Bacteroides acidifaciens as an active ingredient. In addition, the present disclosure relates to a transformant expressing a lean phenotype, in which an Atg7 gene is deleted in dendritic cells.

Claims (3)

1. A method for treating obesity in a subject, the method comprising administering a pharmaceutically-effective amount of Bacteroides acidifaciens to the subject in need of treatment of obesity.

2. A method for treating obesity according to claim 1 , wherein the Bacteroides acidifaciens activates fat oxidation in adipose tissue.

3. A method for treating obesity according to claim 1 , wherein the subject administered the pharmaceutically-effective amount of Bacteroides acidifaciens has a higher amount of intestinal total bacteria as compared to an obese person not administered the pharmaceutically-effective amount of Bacteroides acidifaciens.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2019
From: THE ASAN FOUNDATION
To: GI BIOME
Reel/Frame 048954/0399 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2017
From: KWEON, MI NA; YANG, JIN YOUNG
To: THE ASAN FOUNDATION
Reel/Frame 043257/0895 →
Priority Claims (1)
KR 10-2014-0175349 · Dec 8, 2014 · national
Continuity (1)
Related Publication 20170333492A1 · Nov 23, 2017