IP Library › Granted Patent US 10,830,780
Granted Patent B2
US 10,830,780 · App. 15/539,346 · Granted Nov 10, 2020

Apparatus and methods for sample analysis and classification based on terpenes and cannabinoids in the sample

Inventors: Matthew W. Giese (Westlake Village, CA); Mark Anthony Lewis (Westlake Village, CA)
Assignee: Biotech Institute, LLC
G01N33/948G01N30/68G01N2030/025G01N2030/027G01N2030/884
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Quick Facts
Patent No.
US 10,830,780
App. No.
15/539,346
Granted
Nov 10, 2020
Kind
B2
Abstract

The disclosure relates to systems, apparatuses, and methods for estimating a terpene level of two or more terpenes of the plurality of terpenes in the sample to generate a set of terpene levels; and/or estimating a cannabinoid level of two or more cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels; configured to store a set of groups and classify the sample to a group of the set of groups, based on said terpene and cannabinoid levels. The present disclosure also relates to systems, apparatuses, and methods configured to generate entourage effect values and organoleptic values, based on said cannabinoid and terpene levels.

Claims (63)

1. A kit, comprising:

a chemical analyzer configured to:

(a) receive a sample, the sample including a plurality of terpenes or a plurality of cannabinoids, and

(b) chemically analyze the sample, including:

estimating a terpene level of two or more terpenes of the plurality of terpenes in the sample to generate a set of terpene levels, and

estimating a cannabinoid level of two or more cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels; and

a computing apparatus operatively coupled to the chemical analyzer, the computing apparatus including:

a memory configured to:

receive and store the set of terpene levels and the set of cannabinoid levels, and

store a set of classification groups; and

a processor configured to:

classify the sample to a classification group from the set of classification groups based on the set of terpene levels and the set of cannabinoid levels, the classifying including dividing a relative content of a second-highest accumulating terpene from the plurality of terpenes by a relative content of a primary terpene from the plurality of terpenes to define a modulating factor, the classification group selected based on a comparison of the modulating factor with a predetermined contribution factor, and

transmit an alphanumeric sequence to an output interface of the processor based on the classification group from the set of classification groups, the alphanumeric sequence including a representation of a terpene classification of the sample followed by a representation of a cannabinoid classification of the sample.

2. The kit of claim 1 , wherein the modulating factor is a first modulating factor, the classifying further including dividing a relative content of a third-highest accumulating terpene from the plurality of terpenes by the relative content of the primary terpene to define a second modulating factor, the classification group including the primary terpene and at least one of:

the second-highest accumulating terpene when the first modulating factor is equal to or greater than the predetermined contribution factor; or

the third-highest accumulating terpene when the second modulating factor is equal to or greater than the predetermined contribution factor.

3. The kit of claim 1 , the sample including one or more cannabis species, each cannabis species selected from the group consisting of Cannabis sativa, Cannabis indica , and Cannabis ruderalis.

4. The kit of claim 1 , the processor further configured to classify the sample based on at least one of a highest terpene level of the set of terpene levels, or a highest cannabinoid level of the set of cannabinoid levels.

5. The kit of claim 1 , the processor further configured to classify the sample based on at least one of:

two or more terpene levels of the set of terpene levels, the two or more terpene levels including a first terpene level and a second terpene level, the first terpene level being the highest terpene level of the set of terpene levels, the second terpene level being lesser than the first terpene level and greater than a remainder of the set of terpene levels, or

two or more cannabinoid levels of the set of cannabinoid levels, the two or more cannabinoid levels including a first cannabinoid level and a second cannabinoid level, the first cannabinoid level being the highest cannabinoid level of the set of cannabinoid levels, the second cannabinoid level being lesser than the first cannabinoid level and greater than a remainder of the set of cannabinoid levels.

6. An apparatus, comprising:

a housing;

a chemical analyzer disposed within the housing and configured to:

receive a sample, the sample including a plurality of terpenes and a plurality of cannabinoids;

chemically analyze the sample, including:

estimating a terpene level of two or more terpenes of the plurality of terpenes in the sample to generate a set of terpene levels, and

estimating a cannabinoid level of two or more cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels;

a classifier disposed within the housing and implemented in one of a memory or a processing device, the classifier communicably coupled to the chemical analyzer, the classifier configured to classify the sample to a classification group from a set of classification groups based on the set of terpene levels and the set of cannabinoid levels, the classifying including dividing a relative content of a second-highest accumulating terpene from the plurality of terpenes by a relative content of a primary terpene from the plurality of terpenes to define a modulating factor, the classification group selected based on a comparison of the modulating factor with a predetermined contribution factor; and

a sequence generator disposed within the housing and configured to generate and transmit an alphanumeric sequence based on the classification group from the set of classification groups, the alphanumeric sequence including a representation of a terpene classification of the sample followed by a representation of a cannabinoid classification of the sample.

7. The apparatus of claim 6 , wherein the modulating factor is a first modulating factor, the classifying further including dividing a relative content of a third-highest accumulating terpene from the plurality of terpenes by the relative content of the primary terpene to define a second modulating factor, the classification group including the primary terpene and at least one of:

the second-highest accumulating terpene when the first modulating factor is equal to or greater than the predetermined contribution factor; or

the third-highest accumulating terpene when the second modulating factor is equal to or greater than the predetermined contribution factor.

8. The apparatus of claim 6 , the sample including one or more cannabis species, each cannabis species selected from the group consisting of Cannabis sativa, Cannabis indica , and Cannabis ruderalis.

9. The apparatus of claim 6 , the classifier further configured to classify the sample based on at least one of: a highest terpene level of the set of terpene levels, or a highest cannabinoid level of the set of cannabinoid levels.

10. The apparatus of claim 6 , the classifier further configured to classify the sample based on at least one of:

at least two terpene levels of the set of terpene levels, the at least two terpene levels including a first terpene level and a second terpene level, the first terpene level being the highest terpene level of the set of terpene levels, the second terpene level being lesser than the first terpene level and greater than a remainder of the set of terpene levels, or

at least two cannabinoid levels of the set of cannabinoid levels, the at least two cannabinoid levels including a first cannabinoid level and a second cannabinoid level, the first cannabinoid level being the highest cannabinoid level of the set of cannabinoid levels, the second cannabinoid level being lesser than the first cannabinoid level and greater than a remainder of the set of cannabinoid levels.

11. The apparatus of claim 6 , the classifier configured to classify the sample using bottom up hierarchical classification.

12. The apparatus of claim 6 , the classifier configured to classify the sample using a agglomerative hierarchical clustering approach.

13. A method, comprising:

chemically analyzing, via a chemical analyzer, a sample including a plurality of terpenes and a plurality of cannabinoids, the chemically analyzing including:

estimating a terpene level of at least two terpenes of the plurality of terpenes in the sample to generate a set of terpene levels, and

estimating a cannabinoid level of at least two cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels;

classifying the sample to a classification group from a set of classification groups based on the set of terpene levels and the set of cannabinoid levels, the classifying including dividing a relative content of a second-highest accumulating terpene from the plurality of terpenes by a relative content of a primary terpene from the plurality of terpenes to define a modulating factor, the classification group selected based on a comparison of the modulating factor with a predetermined contribution factor; and

transmitting an alphanumeric sequence based on the classification group from the set of classification groups, the alphanumeric sequence including a representation of a terpene classification of the sample followed by a representation of a cannabinoid classification of the sample.

14. The method of claim 13 , wherein the modulating factor is a first modulating factor, the classifying further including dividing a relative content of a third-highest accumulating terpene from the plurality of terpenes by the relative content of the primary terpene to define a second modulating factor.

15. The method of claim 14 , wherein the classification group includes the primary terpene and at least one of:

the second-highest accumulating terpene when the first modulating factor is equal to or greater than the predetermined contribution factor; or

the third-highest accumulating terpene when the second modulating factor is equal to or greater than the predetermined contribution factor.

16. The method of claim 13 , the sample including one or more cannabis species, each cannabis species selected from the group consisting of Cannabis sativa, Cannabis indica , and Cannabis ruderalis.

17. The method of claim 13 , the classifying including classifying the sample based on at least one of: a highest terpene level of the set of terpene levels, or a highest cannabinoid level of the set of cannabinoid levels.

18. The method of claim 13 , the classifying the sample based on at least one of:

at least two terpene levels of the set of terpene levels, the at least two terpene levels including a first terpene level and a second terpene level, the first terpene level being the highest terpene level of the set of terpene levels, the second terpene level being lesser than the first terpene level and greater than a remainder of the set of terpene levels, or

at least two cannabinoid levels of the set of cannabinoid levels, the at least two cannabinoid levels including a first cannabinoid level and a second cannabinoid level, the first cannabinoid level being the highest cannabinoid level of the set of cannabinoid levels, the second cannabinoid level being lesser than the first cannabinoid level and greater than a remainder of the set of cannabinoid levels.

19. The method of claim 13 , wherein:

the chemically analyzing includes generating the set of terpene levels;

the set of terpene levels is a set of absolute terpene levels; and

the classifying includes:

generating a set of relative terpene levels based on the set of absolute terpene levels, and

classifying the sample based on the set of relative terpene levels.

20. The method of claim 13 , wherein the classifying includes classifying the sample using an agglomerative hierarchical clustering (AHC) analysis.

21. The method of claim 20 , wherein the classifying further includes pruning the AHC analysis after detecting 40% similarity between members of the classification group.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 20, 2018
From: GIESE, MATTHEW W.; LEWIS, MARK ANTHONY
To: BIOTECH INSTITUTE, LLC
Reel/Frame 046635/0470 →
Continuity (2)
Provisional Application 62107652 · Jan 26, 2015
Related Publication 20180284145A1 · Oct 4, 2018