IP Library Granted Patent US 11,072,592
Granted Patent B2
US 11,072,592 · App. 15/553,353 · Granted Jul 27, 2021

Small molecules that enable cartilage rejuvenation

Inventors: Denis Evseenko (Tarzana, CA); Benjamin J. Van Handel (Los Angeles, CA); Varghese John (Los Angeles, CA)
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
C07D277/42C07D417/04
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Quick Facts
Patent No.
US 11,072,592
App. No.
15/553,353
Granted
Jul 27, 2021
Kind
B2
Abstract

There are provided, inter alia, methods and compounds for activating a proliferative program in competent adult chondrocytes.

Claims (5)

1. A compound selected from:

2. The compound of claim 1 , wherein the structure is:

3. The compound of claim 1 , wherein the structure is:

4. The compound of claim 1 , wherein the structure is:

5. The compound of claim 1 , wherein the structure is:

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME AND THIRD INVENTOR'S EXECUTION DATE PREVIOUSLY RECORDED ON REEL 046001 FRAME 0006. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 19, 2021
From: JOHN, VARGHESE; EVSEENKO, DENIS; VAN HANDEL, BENJAMIN J.
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 055665/0479 →
CONFIRMATORY LICENSE Recorded Nov 15, 2019
From: UNIVERSITY OF CALIFORNIA LOS ANGELES
To: THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY
Reel/Frame 051037/0596 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2018
From: JOHN, VARGHESE; EVSEENKO, DENIS; VAN HANDEL, BENJAMIN J.
To: REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 046001/0006 →
Continuity (2)
Provisional Application 62126010 · Feb 27, 2015
Related Publication 20180244638A1 · Aug 30, 2018