Modular testing device for analyzing biological samples

1. A modular testing device comprising:

a base unit; and

an expansion unit that communicates with the base unit, wherein the expansion unit comprises:

a housing;

a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed; and

an optical assembly positioned in the housing, wherein the optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture, wherein data that is collected in the optical assembly is communicated to the base unit, and wherein the optical assembly of the expansion unit includes an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly.

2. The modular testing device of claim 1 , wherein the expansion unit communicates with the base unit over a hard wire connection.

3. The modular testing device of claim 1 , wherein the expansion unit communicates with the base unit over a wireless connection.

4. The modular testing device of claim 1 , wherein the modular testing device includes a plurality of expansion units that each communicate directly with the base unit.

5. The modular testing device of claim 1 , wherein the modular testing device includes a plurality of expansion units, wherein a first expansion unit communicates directly with the base unit and the other expansion units communicate with the base unit through the first expansion unit.

6. The modular testing device of claim 1 , wherein the base unit comprises:

a housing with an integrated touchscreen display;

a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed; and

an optical assembly positioned in the housing, wherein the optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture; and

an electronic assembly that is configured to receive data from the optical assembly and transmit it for display on the touchscreen display; and

a power supply in the housing to power the base unit.

7. The modular testing device of claim 6 , wherein the optical assembly of the base unit includes an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly.

8. The modular testing device of claim 1 , wherein the base unit is a computer selected from the group consisting of a desktop computer, a laptop computer, a tablet computer, a mobile phone, a smart watch, and an embedded PC.

9. The modular testing device of claim 1 , wherein the expansion unit further comprises:

an electronic assembly that is configured to receive data from the optical assembly and transmit it to the base unit; and

a power supply in the housing to power the expansion unit.

10. A modular testing device comprising:

a base unit that comprises:

a housing with an integrated touchscreen display;

a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed; and

an optical assembly positioned in the housing, wherein the optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture; and

an expansion unit that communicates with the base unit, wherein the expansion unit comprises:

a housing;

a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed; and

an optical assembly positioned in the housing, wherein the optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture, and wherein the optical assembly in the expansion unit comprises:

a heating component to heat the biological sample and reagent mixture in the sample holder;

a plurality of light-emitting diodes configured to excite the biological sample and reagent mixture in the sample holder, wherein the plurality of light-emitting diodes are positioned on a first side of an excitation filter that extends across the entire optical assembly and the sample holder is positioned on a second side of the excitation filter; and

a plurality of photodetectors configured to detect a signal from the biological sample and reagent mixture in the sample holder, wherein the plurality of photodetectors are positioned on a first side of an emission filter that extends across the entire optical assembly and the sample holder is positioned on a second side of the emission filter.

11. The modular testing device of claim 10 , wherein the base unit further comprises:

an integrated handle to allow for transport of the base unit;

a lid over the receptacle that is movable between an open and closed position;

an electronic assembly that is configured to receive data from the optical assembly and transmit it for display on the touchscreen display, and that is configured to receive data from the expansion unit and transmit it for display on the touchscreen display;

a power supply in the housing to power the base unit; and

a machine readable code reader in the housing for reading a machine readable code.

12. The portable testing device of claim 10 , wherein the optical assembly in the base unit comprises:

a heating component to heat the biological sample and reagent mixture in the sample holder;

a plurality of light-emitting diodes to excite the biological sample and reagent mixture in the sample holder, wherein the plurality of light-emitting diodes are positioned on a first side of an excitation filter that extends across the entire optical assembly and the sample holder is positioned on a second side of the excitation filter; and

a plurality of photodetectors to detect a signal from the biological sample and reagent mixture in the sample holder, wherein the plurality of photodetectors are positioned on a first side of an emission filter that extends across the entire optical assembly and the sample holder is positioned on a second side of the emission filter.

13. The modular testing device of claim 10 , wherein the expansion unit further comprises:

an electronic assembly that is configured to receive data from the optical assembly and transmit it to the base unit; and

a power supply in the housing to power the expansion unit.

14. A method of analyzing a biological sample and reagent mixture in a modular testing device, the method comprising:

preparing a biological sample and reagent mixture for testing and placing the biological sample and reagent mixture in a sample holder;

placing the sample holder in a receptacle in an expansion unit, wherein the expansion unit comprises an optical assembly comprising an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly;

beginning an excitation and detection test sequence with the optical assembly to analyze the biological sample and reagent mixture in the expansion unit;

collecting data from the biological sample and reagent mixture in the expansion unit, wherein the data that is collected is collected by the optical assembly; and

communicating the data from the expansion unit to a base unit.

15. The method of claim 14 , wherein communicating the data from the expansion unit to the base unit includes communicating the data over a hard wired connection between the expansion unit and the base unit.

16. The method of claim 14 , wherein communicating the data from the expansion unit to the base unit includes communicating the data over a wireless connection between the expansion unit and the base unit.

17. The method of claim 14 , and further comprising:

processing the data in the expansion unit;

processing the data in the base unit; and

displaying the data on a screen of the base unit.

18. The method of claim 14 , and further comprising:

turning on the base unit and the expansion unit;

selecting the test protocol in the base unit;

communicating the selected test protocol from the base unit to the expansion unit; and

pre-heating the expansion unit in accordance with the selected test protocol.