IP Library Granted Patent US 10,962,755
Granted Patent B2
US 10,962,755 · App. 15/568,213 · Granted Mar 30, 2021

Compact microscope

Inventors: Achillefs Kapanidis (Oxford Oxfordshire, GB); Bo Jing (Oxford Oxfordshire, GB)
Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
G02B21/26G02B21/04G02B21/125G02B21/16G02B21/24G02B21/28G02B21/361G02B21/362
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,962,755
App. No.
15/568,213
Granted
Mar 30, 2021
Kind
B2
Abstract

A compact microscope including an enclosure, a support element, a primary optical support element located within the enclosure and supported by the support element, at least one vibration isolating mount between the support element and the primary optical support element, a sample stage supported on the primary optical support element to support a sample, a return optical system to receive returned light from a sample and transmit returned light to a detection apparatus, wherein the return optical system is mounted on the primary optical support element, and wherein the compact microscope include a at least one of the following elements; a) an objective lens system, b) a temperature-control system, and c) the return optical system being operable to separate returned light into at least a first wavelength band and a second wavelength band.

Claims (35)

1. A compact microscope comprising;

an enclosure,

a support element,

a primary optical support element located within the enclosure and supported by the support element,

at least one vibration isolating mount between the support element and the primary optical support element,

a sample stage supported on the primary optical support element to support a sample,

a return optical system to receive returned light from a sample and transmit returned light to a detection apparatus,

wherein the return optical system is mounted on the primary optical support element, and wherein the compact microscope comprises:

an objective lens system, the objective lens system being supported on the primary optical support element,

an illumination section,

an illumination optical system to direct an illumination light beam from the illumination section to the sample stage, and

a mirror mounted above the sample stage on a wall or a hatch of the enclosure,

wherein the mirror is arranged so that its reflecting surface is perpendicular to the optical axis defined by the objective lens system, and

wherein the illumination optical system is arranged to direct light through the objective lens system to the mirror.

2. A compact microscope according to claim 1 wherein the enclosure comprises the hatch, the mirror being supported by the hatch.

3. A compact microscope according to claim 2 wherein the illumination optical system is operable to focus the illumination light beam such that the illumination light beam is collimated after passing through the objective lens.

4. A compact microscope according to claim 2 wherein the illumination optical system is operable to focus the illumination light beam such that the illumination light beam is focused on a sample after reflection from the mirror.

5. A compact microscope according to claim 1 wherein the compact microscope comprises a temperature control system,

wherein the temperature control system comprises a temperature control circuit comprising a plurality of fluid-carrying channels within at least one of the enclosure and the primary optical support element, and

wherein the temperature control circuit comprises a temperature control fluid inlet and a temperature control fluid outlet connected to the plurality of channels.

6. A compact microscope according to claim 5 wherein the enclosure is provided with a first temperature control circuit and the primary optical support element is provided with a second temperature control circuit.

7. A compact microscope according to claim 6 wherein an outlet of the second temperature control circuit is connected to the first temperature control circuit.

8. A compact microscope according to claim 5 wherein the detection apparatus comprises a cooling element, a cooling fluid inlet and a cooling fluid outlet.

9. A compact microscope according to claim 8 wherein the enclosure is provided with a first temperature control circuit and the primary optical support element is provided with a second temperature control circuit, and an inlet of the second temperature control circuit is connected to the cooling fluid outlet of the detection apparatus.

10. A compact microscope according to claim 1 , wherein the return optical system is operable to separate returned light into at least a first wavelength band and a second wavelength band,

wherein the detection apparatus comprises an imaging apparatus,

wherein the return optical system comprises a first tube lens to focus returned light in a first wavelength band to a first area of the imaging apparatus and a second tube lens to focus returned light in a second wavelength band to a second area of the imaging apparatus, and

wherein the compact microscope further comprises a first mirror element to direct light from the first tube lens to the first area of the imaging apparatus and a second mirror element to direct light from the second tube lens to the second area of the imaging apparatus.

11. A compact microscope according to claim 10 wherein the first mirror element and second mirror element are close to the imaging apparatus.

12. A compact microscope according to claim 10 further comprising a beam stop adjacent the mirror elements to block undesired parts of the returned light.

13. A compact microscope according to claim 1 , wherein the return optical system is operable to separate returned light into at least a first wavelength band and a second wavelength band,

wherein the detection apparatus comprises an imaging apparatus,

wherein the return optical system comprises a first tube lens to focus returned light in a first wavelength band to a first area of the imaging apparatus and a second tube lens to focus returned light in a second wavelength band to a second area of the imaging apparatus, and

wherein the first tube lens is moveable independently of the second tube lens and the second tube lens is moveable independently of the first tube lens.

14. A compact microscope system according to claim 1 wherein the illumination source comprises a laser source.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2020
From: KAPANIDIS, ACHILLEFS; JING, BO
To: OXFORD UNIVERSITY INNOVATION LIMITED
Reel/Frame 053642/0808 →
Priority Claims (1)
GB 1507021 · Apr 24, 2015 · national
Continuity (1)
Related Publication 20180143418A1 · May 24, 2018