IP Library Granted Patent US 10,253,339
Granted Patent B2
US 10,253,339 · App. 15/568,385 · Granted Apr 9, 2019

Gluconate repressor variant, microorganism containing the same producing L-lysine, and method for producing L-lysine

Inventors: Sang Hee Park (Seoul, KR); Hyung Joon Kim (Seoul, KR); Nam Hyun Kim (Yangsan-si, KR); Jun Ok Moon (Seoul, KR); Jeong Seok Oh (Seoul, KR); Song-Gi Ryu (Suwon-si, KR); Hyang Choi (Seoul, KR)
Assignee: CJ CHEILJEDANG CORPORATION
C12P13/08C07C229/26C07K14/195C07K14/34C12N15/77
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Quick Facts
Patent No.
US 10,253,339
App. No.
15/568,385
Granted
Apr 9, 2019
Kind
B2
Abstract

The present invention relates to a novel gluconate repressor variant, a microorganism containing the same, and a method for producing L-lysine using the same.

Claims (12)

1. An isolated and/or recombinant polypeptide having gluconate repressor activity comprising the amino acid sequence of SEQ ID NO: 1.

2. An isolated and/or recombinant polynucleotide encoding the polypeptide of claim 1 .

3. The isolated and/or recombinant polynucleotide of claim 2 , wherein the polynucleotide comprises the nucleotide sequence of SEQ ID NO: 2.

4. An expression vector comprising the polynucleotide of claim 2 .

5. A microorganism of the genus Corynebacterium producing L-lysine, expressing the polypeptide of claim 1 .

6. The microorganism of the genus Corynebacterium of claim 5 , wherein the microorganism of the genus Corynebacterium is Corynebacterium glutamicum.

7. A method for producing L-lysine, comprising

(a) culturing the microorganism of the genus Corynebacterium of claim 5 in a medium; and

(b) recovering L-lysine from the cultured microorganism or the medium in step (a).

8. A method for producing L-lysine, comprising

(a) culturing the microorganism of the genus Corynebacterium of claim 6 in a medium; and

(b) recovering L-lysine from the cultured microorganism or the medium in step (a).

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 2, 2018
From: PARK, SANG HEE; KIM, HYUNG JOON; KIM, NAM HYUN; MOON, JUN OK; OH, JEONG SEOK; RYU, SONG-GI; CHOI, HYANG
To: CJ CHEILJEDANG CORPORATION
Reel/Frame 044516/0109 →
Priority Claims (1)
KR 10-2015-0055495 · Apr 20, 2015 · national
Continuity (1)
Related Publication 20180100173A1 · Apr 12, 2018