IP Library Granted Patent US 10,786,547
Granted Patent B2
US 10,786,547 · App. 15/570,342 · Granted Sep 29, 2020

Compositions, articles of manufacture and methods for treating cancer

Inventors: Amnon Peled (Tel-Aviv, IL); Yaron Pereg (Shoham, IL)
Assignees: Biokine Therapeutics Ltd.; BioLineRx Ltd.
A61K38/1761A61K38/04A61K38/10A61K38/395A61K39/12A61K39/3955A61K47/646A61P35/00C07K16/2818C07K16/2827C07K16/30A61K2039/55522C07K2317/76
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Quick Facts
Patent No.
US 10,786,547
App. No.
15/570,342
Granted
Sep 29, 2020
Kind
B2
Abstract

A method of treating cancer in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a peptide having an amino acid sequence as set forth in SEQ ID NO: 1 or an analog or derivative thereof; and an anti-cancer agent, thereby treating the cancer in the subject.

Claims (3)

1. A method of treating a non-solid tumor cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a peptide having an amino acid sequence as set forth in SEQ ID NO: 1 and an Adenosine A2a receptor antagonist, wherein said antagonist is a small molecule that directly binds said Adenosine A2a receptor.

2. The method of claim 1 , wherein said non-solid tumor is selected from the group consisting of multiple myeloma and leukemia.

3. The method of claim 1 , wherein said peptide and said Adenosine A2a receptor antagonist are co-formulated in a pharmaceutical composition.

Assignments (3)
SECURITY INTEREST Recorded Oct 8, 2018
From: BIOLINE RX LTD.
To: KREOS CAPITAL V (EXPERT FUND) L.P.
Reel/Frame 047088/0803 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2017
From: PELED, AMNON
To: BIOKINE THERAPEUTICS LTD.
Reel/Frame 044140/0975 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2017
From: PEREG, YARON
To: BIOLINERX LTD.
Reel/Frame 044141/0177 →
Continuity (5)
Provisional Application 62193201 · Jul 16, 2015
Provisional Application 62259182 · Nov 24, 2015
Provisional Application 62291039 · Feb 4, 2016
Provisional Application 62291006 · Feb 4, 2016
Related Publication 20180140670A1 · May 24, 2018
Cited By (1)
US 12,291,570