IP Library Granted Patent US 10,933,010
Granted Patent B2
US 10,933,010 · App. 15/572,205 · Granted Mar 2, 2021

External dermal agent

Inventors: Mutsuko Taniguchi (Okayama, JP); Go Takikawa (Okayama, JP); Kiyomi Aizawa (Okayama, JP); Tatsuya Ishihara (Okayama, JP)
Assignee: Hayashibara Co., Ltd.
A61K8/73A61K8/39A61K8/8152A61Q19/00A61Q19/08A61K2800/546
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Quick Facts
Patent No.
US 10,933,010
App. No.
15/572,205
Granted
Mar 2, 2021
Kind
B2
Abstract

[Object] The present invention aims to provide an external dermal agent that tightens the skin, lifts up sagging skin, has no stickiness to the skin, and has a satisfactory compatibility with the skin, without giving any unfavorable feeling to users. [Means to Attain the Object] The present invention solves the above object by providing an external dermal agent characterized in that it contains pullulan and an alkaline-swelling polymer in a mass ratio of the pullulan to the alkaline-swelling polymer being 10 or more.

Claims (10)

1. An external dermal agent, which comprises pullulan and an alkaline-swelling polymer as the only active ingredients to lift up the skin of the face, wherein said pullulan is in an amount of 2 to 5% by mass to the total mass of the external dermal agent, and the mass ratio of said pullulan to said alkaline-swelling polymer is in the range of 50 to 125.

2. The external dermal agent of claim 1 , wherein said alkaline-swelling polymer is one or more members selected from the group consisting of acrylic acid and methacrylic acid as a monomer, or a copolymer and/or a crosspolymer comprising one or more members selected from the group consisting of an acrylic acid derivative having a hydrophobic group intramolecularly and a methacrylic acid derivative having a hydrophobic group intramolecularly.

3. The external dermal agent of claim 1 , wherein said alkaline-swelling polymer is an acrylates/alkyl acrylate crosspolymer.

4. The external dermal agent of claim 1 , which further contains a non-ionic surfactant.

5. The external dermal agent of claim 4 , wherein said non-ionic surfactant is a polyoxyethylene glycerin.

6. A method for lifting up sagging skin of a subject in need thereof, which comprises a step of applying an external dermal agent comprising pullulan and an alkaline-swelling polymer as the only active ingredients to lift up the skin of the face, wherein said pullulan is in an amount of 2 to 5% by mass to the total mass of the external dermal agent, and the mass ratio of said pullulan to said alkaline-swelling polymer is in the range of 50 to 125.

7. The method of claim 6 , wherein said alkaline-swelling polymer is one or more members selected from the group consisting of acrylic acid and methacrylic acid as a monomer, or a copolymer and/or a crosspolymer comprising one or more members selected from the group consisting of an acrylic acid derivative having a hydrophobic group intramolecularly and a methacrylic acid derivative having a hydrophobic group intramolecularly.

8. The method of claim 6 , wherein said alkaline-swelling polymer is an acrylates/alkyl acrylate crosspolymer.

9. The method of claim 6 , wherein said external dermal agent further contains a non-ionic surfactant.

10. The method of claim 9 , wherein said non-ionic surfactant is a polyoxyethylene glycerin.

Assignments (2)
CHANGE OF NAME Recorded Mar 18, 2025
From: HAYASHIBARA CO., LTD.
To: NAGASE VIITA CO., LTD.
Reel/Frame 070538/0828 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2017
From: TANIGUCHI, MUTSUKO; TAKIKAWA, GO; AIZAWA, KIYOMI; ISHIHARA, TATSUYA
To: HAYASHIBARA CO., LTD.
Reel/Frame 044049/0494 →
Priority Claims (1)
JP JP2015-096839 · May 11, 2015 · national
Continuity (1)
Related Publication 20180116940A1 · May 3, 2018