IP Library Granted Patent US 10,750,690
Granted Patent B2
US 10,750,690 · App. 15/577,588 · Granted Aug 25, 2020

Reduced gluten grains and compositions thereof

Inventors: Charles Paul Moehs (Seattle, WA); William J. Austill (Seattle, WA); Dayna Loeffler (Seattle, WA); Jessica Mullenberg (Seattle, WA)
Assignee: ARCADIA BIOSCIENCES, INC.
A01H1/06A01H5/10A01H6/4678A23L7/198C07K14/415A23V2002/00
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Quick Facts
Patent No.
US 10,750,690
App. No.
15/577,588
Granted
Aug 25, 2020
Kind
B2
Abstract

Plants with reduced gluten grains and compositions thereof are disclosed herein.

Claims (13)

1. A wheat plant comprising one or more mutations in a wheat prolamin box binding factor (WPBF) gene in at least the B genome, wherein the WPBF gene of the B genome codes for a WPBF protein having a tryptophan to a stop codon substitution at position 70 of SEQ ID NO. 6, wherein the one or more mutations contributes to grain from said wheat plant having reduced gluten as compared to grain from a wild type plant.

2. The wheat plant of claim 1 , wherein the one or more mutations in the WPBF gene is in the A and B genomes.

3. The wheat plant of claim 1 , wherein the one or more mutations in the WPBF gene is in the A and D genomes.

4. The wheat plant of claim 1 , wherein the one or more mutations in the WPBF gene is in the A, B, and D genomes.

5. The wheat plant of claim 1 , wherein the one or more mutations results in reduced low molecular weight glutenins in grain from said wheat plant relative to grain from a wild-type wheat plant.

6. The wheat plant of claim 1 , wherein the one or more mutations results in reduced gliadins in grain from said wheat plant relative to grain from a wild type wheat plant.

7. The wheat plant of claim 1 , wherein the one or more mutations results in increased or unaltered high molecular weight glutenins in grain from said wheat plant relative to grain from a wild type wheat plant.

8. The wheat plant of claim 1 , further comprising one or more mutations that result in an amino acid change in the WPBF protein selected from the amino acid changes recited in Tables 1-3.

9. Wheat grain from the wheat plant of claim 1 .

10. Flour comprising the wheat grain of claim 9 .

11. A food product comprising a component of the wheat plant of claim 1 .

12. A wheat seed, plant part or progeny thereof from the wheat plant of claim 1 , wherein said progeny comprises the one or more mutations in the WPBF gene of the B genome.

13. The wheat plant of claim 2 , wherein the WPBF gene of the A genome codes for a WPBF protein having a cysteine to tyrosine substitution at position 66 of SEQ ID NO. 3.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2025
From: ARCADIA BIOSCIENCES, INC.
To: BIOCERES CROP SOLUTIONS, CORP.
Reel/Frame 070668/0847 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 3, 2018
From: MOEHS, CHARLES PAUL; AUSTILL, WILLIAM J., II; LOEFFLER, DAYNA L.; MULLENBERG, JESSICA C.
To: ARCADIA BIOSCIENCES, INC.
Reel/Frame 046259/0107 →
CONFIRMATORY LICENSE Recorded Jan 23, 2018
From: ARCADIA BIOSCIENCES, INC.
To: US. GOVERNMENT, AS REPRESENTED BY THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Reel/Frame 045127/0743 →
Continuity (4)
Provisional Application 62168536 · May 29, 2015
Provisional Application 62263912 · Dec 7, 2015
Provisional Application 62327822 · Apr 26, 2016
Related Publication 20190000025A1 · Jan 3, 2019