Thin-film cuff for endothelialization of endovascular grafts
Methods and devices are provided for the use of thin-film cuffs on endovascular grafts. A method includes forming a fenestrated thin-film Nitinol sheet, expanding the fenestrated thin-film Nitinol sheet to expand the fenestrations, and attaching the expanded thin-film Nitinol sheet to a longitudinal end of a cover for an endovascular graft to form a cuff for the endovascular graft. The method may further include implanting the endovascular graft into a blood vessel. An endovascular graft may include a cover having a proximal and distal end, a proximal thin-film mesh cuff extending from the proximal end, and a distal thin-film mesh cuff extending form the distal end.
1. An endovascular graft, comprising:
a tubular cover extending along a longitudinal axis and having a circular cross-section,
wherein the tubular cover is at least one of an impermeable cover or a woven fabric cover; and
a fenestrated thin-film cuff having a circular cross-section and attached to a longitudinal end of the tubular cover such that the fenestrated thin-film cuff is attached to the tubular cover, the fenestrated thin-film cuff is formed from a first Nitinol layer deposited on a second Nitinol layer with a sacrificial layer removed from between the first and the second Nitinol layers.
2. The endovascular graft of claim 1 , further comprising:
an additional fenestrated thin-film cuff having a circular cross-section and extending from an opposing longitudinal end of the tubular cover.
3. The endovascular graft of claim 1 , wherein the fenestrated thin-film cuff comprises a fenestrated thin-film Nitinol sheet.
4. The endovascular graft of claim 1 , wherein the fenestrated thin-film cuff comprise a two-dimensional fenestrated thin-film sheet.
5. The endovascular graft of claim 1 , wherein the fenestrated thin-film cuff comprise a three-dimensional fenestrated thin-film sheet having a circular cross-section with a radius that is equal or approximately equal to a radius of a circular cross-section of the tubular cover.
6. The endovascular graft of claim 1 , wherein the fenestrated thin-film cuff has a thickness of between 4 and 30 microns, wherein each fenestration of the fenestrated thin-film cuff has a length of between 100 and 500 microns before expansion, and wherein each strut of the fenestrated thin-film cuff has a width of between 4 microns and 30 microns.
7. The endovascular graft of claim 1 , wherein the fenestrated thin-film cuff is attached to a luminal surface of the tubular cover and/or an outer surface of the tubular cover.
8. The endovascular graft of claim 1 , further comprising:
a stent backbone, wherein the thin-film cuffed cover is attached to the stent backbone.