Lens oil having a narrow molecular weight distribution for intraocular lens devices

1. A silicone oil having a mean molecular weight in a range from about 20,000 Daltons to about 400,000 Daltons, wherein no more than about 3% to about 4% of the total silicone oil by weight is comprised of components having a molecular weight less than about 15,000 Daltons, the total silicone oil by weight is comprised of components having a molecular weight greater than about 5,000 Daltons, wherein the silicone oil has a viscosity of about 15,000 mm 2 /s or greater at 25° C., and wherein the silicone oil comprises a co-polymer comprising diphenylsiloxane and dimethylsiloxane.

2. The silicone oil of claim 1 , wherein the silicone oil has a viscosity of about 15,000 mm 2 /s to about 100,000 mm 2 /s at 25° C.

3. The silicone oil of claim 1 , wherein the silicone oil has a refractive index of about 1.49.

4. The silicone oil of claim 1 , wherein the silicone oil has a polydispersity index of about 1.5 or greater.

5. The silicone oil of claim 1 , wherein the silicone oil comprises about 22 mole % to about 25 mole % diphenylsiloxane and about 78 mole % to about 75 mole % dimethylsiloxane.

6. The silicone oil of claim 1 , wherein the silicone oil comprises about 20 mole % to about 25 mole % diphenylsiloxane and about 80 mole % to about 75 mole % of dimethylsiloxane.

7. An intraocular lens (IOL) device, comprising:

an anterior region;

a posterior region;

a cavity region defined between the anterior and posterior regions; and

a fluid disposed in the cavity region, the fluid comprising a silicone oil having a mean molecular weight greater than about 20,000 Daltons, wherein no more than about 3% to about 4% of the total silicone oil by weight is comprised of components having a molecular weight less than about 15,000 Daltons.

8. The IOL device of claim 7 , wherein the silicone oil has no component having a molecular weight less than about 5,000 Daltons.

9. The IOL device of claim 7 , wherein the silicone oil has a viscosity of about 4,000 mm 2 /s at 25° C. or greater.

10. The IOL device of claim 7 , wherein the silicone oil has a refractive index of about 1.49.

11. The IOL device of claim 7 , wherein the silicone oil has a polydispersity index of about 1.5 or greater.

12. The IOL device of claim 7 , wherein the silicone oil comprises diphenyl siloxane and dimethylsiloxane.

13. The IOL device of claim 12 , wherein the silicone oil comprises about 20 mole % to about 25 mole % of diphenylsiloxane and about 80 mole % to about 75 mole % of dimethylsiloxane.

14. The IOL device of claim 7 , wherein the anterior portion comprises a refractive optical element, and wherein at least a portion of the posterior portion comprises an elastic material configured to actuate in response to a force applied thereto, causing the fluid to exert a deforming or displacing force on the refractive optical element.

15. The IOL device of claim 7 , wherein at least one of the anterior region and the posterior region comprises a bulk polymeric material.

16. An intraocular (IOL) device configured for implantation in a lens capsule of a patient's eye, the IOL device comprising:

a silicone oil having a mean molecular weight greater than about 20,000 Daltons, wherein the silicone oil is purified such that no component thereof has a molecular weight less than about 5,000 Daltons, and

a bulk polymeric material, wherein at least a portion of the bulk material is in physical contact with the silicone oil.

17. The IOL device of claim 16 , wherein the silicone oil is entirely encapsulated by the bulk polymeric material.

18. The IOL device of claim 16 , wherein the bulk polymeric material is a fluorosilicone polymer may be represented by formula (I):

where n and m are each independently 0 to about 500; t is about 100 to about 1000; each R 1 is independently alkyl or aryl; R 2 is haloalkyl; R 3 is alkyl or haloalkyl; R 4 and R 5 are independently alkyl, haloalkyl or aryl; and each X is a crosslinker that links the polymer of formula (I) with a second polymer of formula (I).

19. The IOL device of claim 18 , wherein the crosslinker, X, is a methylhydrosiloxane-dimethylsiloxane copolymer with a methyl-hydrogen content of from about 30 to about 70 mole %.

20. The IOL device of claim 16 , wherein the silicone oil is purified using supercritical fluid extraction.