Composition for promoting metallothionein production
View Patent ↗The present disclosure relates to a composition to aid in heavy metal detox. Metallothioneins (MT) are a family of cysteine-rich enzymes in the body that help remove and regulate heavy metals, copper, and other metals. Amino Acids in combination with zinc and/or molybdenum may provide improved production of MT over amino acid or zinc supplements alone. Additionally, Vitamin B6, Molybdenum, and Boron may be included to further enhance the efficacy of the composition.
1. A composition for reducing heavy metal accumulation in a user, the composition comprising:
an amino acid;
an effective amount of molybdenum chelate for forming a molybdenum cofactor to serve as a catalytic site for molybdenum enzymes in the user;
pyridoxine;
an effective amount of zinc for regulating pyridoxine metabolism in the user; and
reduced glutathione (GSH);
wherein the composition promotes increased production of metallothionein in the user wherein the amino acid is an effective amount of an amino acid selected from the group consisting of n-acetylcysteine, serine, and glutamine for increasing production of glutathione in the user.
2. The composition of claim 1 , wherein the effective amount of zinc is an effective amount of zinc amino acid chelate “AAC” having a potency between about 15% and about 32%.
3. The composition of claim 1 , wherein the molybdenum chelate has a potency between about 12% and about 30%.
4. The composition of claim 1 , further comprising cellulose, magnesium stearate, and dicalcium phosphate.
5. The composition of claim 1 , wherein the reduced glutathione (GSH) is present in an amount effective for reducing a concentration of copper in the user.
6. The composition of claim 1 , wherein the effective amount of zinc has a potency between about 15% and about 32% and an amount between about 10 mg and about 100 mg.
7. The composition of claim 1 , wherein the effective amount of molybdenum chelate has a potency between about 12% and about 30% and an amount between about 0.015 mg and about 0.2 mg.
8. The composition of claim 1 , wherein the pyridoxine has a potency between about 70% and about 95% and an amount between about 18 mg and about 170 mg.
9. The composition of claim 1 , wherein the amino acid comprises serine.
10. The composition of claim 1 , wherein the amino acid has a potency between about 90% and about 100% and an amount between about 25 mg and about 500 mg.
11. A composition for reducing heavy metal accumulation in a human, the composition comprising:
an effective amount of zinc picolinate for regulating vitamin B6 metabolism in the human;
an effective amount of a bio-available form of molybdenum chelate for forming a molybdenum cofactor to serve as a catalytic site for molybdenum enzymes in the human;
pyridoxine;
an effective amount of boron for increasing production of ceruloplasmin in the human;
reduced glutathione (GSH); and
at least one amino acid;
wherein the composition promotes increased production of metallothionein in the human wherein the at least one amino acid is an effective amount of an amino acid selected from the group consisting of n-acetylcysteine, serine, and glutamine for increasing production of glutathione in the user.
12. The composition of claim 11 , wherein the effective amount of the bio-available form of molybdenum chelate has a potency between about 12% and about 30% and an amount between about 0.015 mg and about 0.2 mg.
13. The composition of claim 11 , wherein the pyridoxine has a potency between about 70% and about 95% and an amount between about 18 mg and about 170 mg.
14. The composition of claim 11 , wherein the at least one amino acid is serine.
15. The composition of claim 14 , wherein the at least one amino acid has a potency between about 90% and about 100% and an amount between about 25 mg and about 500 mg.
16. The composition of claim 11 , wherein the effective amount of zinc picolinate has a potency between about 15% and about 32% and an amount between about 10 mg and about 100 mg.
17. The composition of claim 11 , wherein the effective amount of boron is in an amount of less than about 3 mg.
18. The composition of claim 1 , further comprising an effective amount of boron for increasing production of ceruloplasmin in the user.