IP Library Granted Patent US 10,167,314
Granted Patent B2
US 10,167,314 · App. 15/614,134 · Granted Jan 1, 2019

Methods of treating depression and other related diseases

Inventor: Joseph R. Moskal (Evanston, IL)
Assignee: Northwestern University
C07K5/1013A61K38/07A61K45/06C07K5/06139C07K5/081C07K5/0821
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Quick Facts
Patent No.
US 10,167,314
App. No.
15/614,134
Granted
Jan 1, 2019
Kind
B2
Abstract

The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.

Claims (8)

1. A method for treating a patient suffering from postpartum depression comprising administering to said patient an effective amount of a GLYX-13 peptide represented by formula:

or a pharmaceutically acceptable salt thereof.

2. A method for treating a patient suffering from a post-traumatic stress disorder comprising administering to said patient an effective amount of a GLYX-13 peptide represented by formula:

or a pharmaceutically acceptable salt thereof.

3. A method for treating a patient suffering from a depression comprising administering to said patient an effective amount of a GLYX-13 peptide represented by formula:

or a pharmaceutically acceptable salt thereof.

4. The method according to claim 3 wherein said patient is at risk of suicide.

5. The method according to claim 3 wherein said patient experiences or exhibits symptoms of depression selected from hopelessness, self-harm or suicide, an absence of positive thoughts or plans, or a combination thereof.

Assignments (2)
SECURITY INTEREST Recorded Dec 18, 2024
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 069742/0846 →
SECURITY INTEREST Recorded Nov 6, 2023
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 065473/0327 →
Continuity (7)
Continuation 14616220 · Feb 6, 2015
Continuation 13440368 · Apr 5, 2012
Continuation In Part PCTUS2010051415 · Oct 5, 2010
Provisional Application 61507252 · Jul 13, 2011
Provisional Application 61471942 · Apr 5, 2011
Provisional Application 61248650 · Oct 5, 2009
Related Publication 20180094026A1 · Apr 5, 2018