IP Library › Granted Patent US 10,294,214
Granted Patent B2
US 10,294,214 · App. 15/616,578 · Granted May 21, 2019

Positive allosteric modulators of human melanocortin-4 receptor

Inventors: Roger D. Cone (Nashville, TN); Michael J. Bishop (San Diego, CA); Eugene L. Stewart (Malvern, PA); Lawrence A. Wolfe (Collegeville, PA); Jaques Pantel (Paris, FR); Julien Sebag (Iowa City, IA); C. David Weaver (Nashville, TN); Savannah Williams (Nashville, TN); Helen Cox (London, GB); Iain Tough (London, GB); Luis Diaz Gimenez (Nashville, TN); Subramanian Baskaran (Cary, NC)
Assignees: Vanderbilt University; King's College London; Glaxo Group Limited
C07D401/12A61K31/4439A61K31/454A61K31/496A61K31/5377A61K38/34A61K45/06
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Quick Facts
Patent No.
US 10,294,214
App. No.
15/616,578
Granted
May 21, 2019
Kind
B2
Abstract

Disclosed herein are positive allosteric modulators of melanocortin receptor and methods of using such modulators.

Claims (4)

1. A compound selected from the group consisting of

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition, comprising: the compound claim 1 and a pharmaceutically acceptable carrier.

3. A compound of clam 1 , wherein the compound is

Assignments (5)
CONFIRMATORY LICENSE Recorded Jul 5, 2018
From: VANDERBILT UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 046499/0073 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR IAN TOUGH TO IAIN TOUGH PREVIOUSLY RECORDED ON REEL 044713 FRAME 0212. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 26, 2018
From: COX, HELEN; TOUGH, IAIN
To: KING'S COLLEGE LONDON
Reel/Frame 045167/0796 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2018
From: BISHOP, MICHAEL J.; STEWART, EUGENE L.; WOLFE, LAWRENCE A.; BASKARAN, SUBRAMANIAN
To: GLAXO GROUP LIMITED
Reel/Frame 044713/0178 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2018
From: CONE, ROGER D.; PATEL, JACQUES; SEBAG, JULIEN; WEAVER, C. DAVID; WILLIAMS, SAVANNAH; GIMENEZ, LUIS DIAZ
To: VANDERBILT UNIVERSITY
Reel/Frame 044713/0197 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2018
From: COX, HELEN; TOUGH, IAN
To: KING'S COLLEGE LONDON
Reel/Frame 044713/0212 →
Continuity (2)
Provisional Application 62346892 · Jun 7, 2016
Related Publication 20170349571A1 · Dec 7, 2017