Cassette system integrated apparatus
A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
1. A dialysis system comprising:
a fluid handling cassette; and
a controller operatively associated with said cassette and configured for controlling fluid flow within said cassette;
the cassette comprising:
a plurality of fluid flowpaths, and a plurality of pneumatically actuated diaphragm valves, said valves controlled by the controller to regulate fluid flow in said plurality of fluid flowpaths;
a first group of one or more flowpaths of the plurality of fluid flowpaths configured to direct water from a water inlet to a dialysate mixing circuit of the dialysis system, the water inlet connected to a water source external to the cassette;
a second group of flowpaths of the plurality of fluid flowpaths configured to direct a dialysate solution from a dialysate solution source to a dialysate holding tank, the dialysate holding tank being external to the cassette;
a third group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate holding tank to a dialysate balancing circuit of the dialysis system; and
a fourth group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate solution source and from the dialysate balancing circuit to a drain.
2. The dialysis system of claim 1 , wherein the cassette comprises an air vent flowpath, the air vent flowpath comprising
(1) a vent inlet port configured to fluidically connect to a vent of the dialysate holding tank;
(2) a vent outlet port configured to vent air to a surrounding atmosphere; and
(3) a venting valve interposed between the vent inlet port and the vent outlet port, wherein
the controller is configured to control the venting valve to permit venting of the dialysate holding tank.
3. The dialysis system of claim 1 , wherein the second group of flowpaths comprises a first dialysate flowpath and the fourth group of flowpaths comprises a first drain flowpath, wherein the first drain flowpath is fluidically connected to a first dialysate outlet port of the cassette, and the first dialysate flowpath comprises a first dialysate valve interposed between a first dialysate inlet port of the cassette and
(1) a second dialysate outlet port of the cassette configured to fluidically connect to the dialysate holding tank, and
(2) a second dialysate valve fluidically connected to the first drain flowpath, wherein
the controller is configured to control the first and second dialysate valves to direct the dialysate solution from the first dialysate inlet port to either the dialysate holding tank or the drain.
4. The dialysis system of claim 3 , wherein the third group of flowpaths comprises a second dialysate flowpath, the second dialysate flowpath comprising a first pneumatically actuated diaphragm pump interposed between a second dialysate inlet port of the cassette and the second dialysate outlet port of the cassette, wherein the controller is configured to control the pump to transfer the dialysate solution from the dialysate holding tank to the dialysate balancing circuit.
5. The dialysis system of claim 4 , further comprising a second pneumatically actuated diaphragm pump interposed between the second dialysate inlet port and the second dialysate outlet port, the second dialysate flowpath including a first pump inlet valve upstream of the first pump, a first pump outlet valve downstream of the first pump, a second pump inlet valve upstream of the second pump, and a second pump outlet valve downstream of the second pump, wherein the controller is configured to control the first and second pumps and the pump valves to pump the dialysate solution with the first and second pumps either sequentially or simultaneously.
6. The dialysis system of claim 4 , wherein the fourth group of flowpaths comprises a second drain flowpath connecting a third dialysate inlet port of the cassette to the first dialysate outlet port, wherein the second drain flowpath comprises a third dialysate valve interposed between the third dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the third dialysate valve to direct the dialysate solution from an outlet of the balancing circuit to the drain.
7. The dialysis system of claim 6 , wherein the fourth group of flowpaths comprises a third drain flowpath connecting a fourth dialysate inlet port of the cassette to the first dialysate outlet port, wherein the third drain flowpath comprises a fourth dialysate valve interposed between the fourth dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the fourth dialysate valve to direct dialysate from an inlet of the dialysate balancing circuit to the drain.
8. The dialysis system of claim 7 , wherein the second dialysate outlet port is configured for fluidic connection to a heater and an ultrafilter positioned upstream of the dialysate balancing circuit, the heater and ultrafilter being external to the cassette, and wherein the controller is configured to control the fourth dialysate valve to direct the dialysate solution from an outlet of the ultrafilter to the drain or to the dialysate holding tank.
9. A dialysis system comprising:
a fluid handling cassette and
a controller operatively associated with said cassette and configured for controlling fluid flow within said cassette;
the cassette comprising:
a plurality of fluid flowpaths, an air vent flowpath, and a plurality of pneumatically actuated diaphragm valves said valves controlled by the controller to regulate fluid flow in said plurality of fluid flowpaths or air flow in said air vent flowpath;
a first group of one or more flowpaths of the plurality of fluid flowpaths configured to direct water from a water inlet to a dialysate mixing circuit of the dialysis system, the water inlet connected to a water source external to the cassette;
a second group of flowpaths of the plurality of fluid flowpaths configured to direct a dialysate solution from dialysate solution source to a dialysate holding tank, the dialysate holding tank being external to the cassette;
a third group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate holding tank to a dialysate balancing circuit of the dialysis system;
a fourth group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate solution source and from the dialysate balancing circuit to a drain;
the air vent flowpath comprising:
(1) a vent inlet port configured to connect to a vent of the dialysate holding tank;
(2) a vent outlet port configured to vent air to a surrounding atmosphere; and
(3) a venting valve interposed between the vent inlet port and the vent outlet port, wherein
the controller is configured to control the venting valve to permit venting of the dialysate holding tank.
10. The dialysis system of claim 9 , wherein the second group of flowpaths comprises a first dialysate flowpath and the fourth group of flowpaths comprises a first drain flowpath, wherein the first drain flowpath is fluidically connected to a first dialysate outlet port of the cassette, and the first dialysate flowpath comprises a first dialysate valve interposed between a first dialysate inlet port of the cassette and
(1) a second dialysate outlet port of the cassette configured to fluidically connect to the dialysate holding tank, and
(2) a second dialysate valve fluidically connected to the first drain flowpath, wherein
the controller is configured to control the first and second dialysate valves to direct the dialysate solution from the first dialysate inlet port to either the dialysate holding tank or the drain.
11. The dialysis system of claim 10 , wherein the third group of flowpaths comprises a second dialysate flowpath, the second dialysate flowpath comprising a first pneumatically actuated diaphragm pump interposed between a second dialysate inlet port of the cassette and the second dialysate outlet port of the cassette, wherein the controller is configured to control the pump to transfer the dialysate solution from the dialysate holding tank to the dialysate balancing circuit.
12. The dialysis system of claim 11 , further comprising a second pneumatically actuated diaphragm pump interposed between the second dialysate inlet port and the second dialysate outlet port, the second dialysate flowpath including a first pump inlet valve upstream of the first pump, a first pump outlet valve downstream of the first pump, a second pump inlet valve upstream of the second pump, and a second pump outlet valve downstream of the second pump, wherein the controller is configured to control the first and second pumps and the pump valves to pump the dialysate solution with the first and second pumps either sequentially or simultaneously.
13. The dialysis system of claim 11 , wherein the fourth group of flowpaths comprises a second drain flowpath connecting a third dialysate inlet port of the cassette to the first dialysate outlet port, wherein the second drain flowpath comprises a third dialysate valve interposed between the third dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the third dialysate valve to direct dialysate from an outlet of the balancing circuit to the drain.
14. The dialysis system of claim 13 , wherein the fourth group of flowpaths comprises a third drain flowpath connecting a fourth dialysate inlet port of the cassette to the first dialysate outlet port, wherein the third drain flowpath comprises a fourth dialysate valve interposed between the fourth dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the fourth dialysate valve to direct dialysate from an inlet of the dialysate balancing circuit to the drain.
15. The dialysis system of claim 14 , wherein the second dialysate outlet port is configured for fluidic connection to a heater and an ultrafilter positioned upstream of the dialysate balancing circuit, the heater and ultrafilter being external to the cassette, and wherein the controller is configured to control the fourth dialysate valve to direct the dialysate solution from an outlet of the ultrafilter to the drain or to the dialysate holding tank.
16. A dialysis system comprising:
a fluid handling cassette and
a controller operatively associated with said cassette and configured for controlling fluid flow within said cassette;
the cassette comprising:
a plurality of fluid flowpaths, and a plurality of pneumatically actuated diaphragm valves, said valves controlled by the controller to regulate fluid flow in said plurality of fluid flowpaths;
a first group of one or more flowpaths of the plurality of fluid flowpaths configured to direct water from a source of water to a dialysate mixing circuit of the dialysis system, the water source being external to the cassette, said first group of one or more flowpaths including a first water flowpath comprising a water inlet of the cassette and a water outlet of the cassette and a water flow valve located between the water inlet and water outlet of the cassette;
a second group of flowpaths of the plurality of fluid flowpaths configured to direct a dialysate solution from a dialysate solution source to a dialysate holding tank, the dialysate holding tank being external to the cassette;
a third group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate holding tank to a dialysate balancing circuit of the dialysis system; and
a fourth group of flowpaths of the plurality of fluid flowpaths configured to direct the dialysate solution from the dialysate solution source and from the dialysate balancing circuit to a drain, wherein;
the controller is configured to control the water flow valve to direct water from the source of water to the dialysate mixing circuit.
17. The dialysis system of claim 16 , wherein the cassette comprises an air vent flowpath, the air vent flowpath comprising
(1) a vent inlet port configured to fluidically connect to a vent of the dialysate holding tank;
(2) a vent outlet port configured to vent air to a surrounding atmosphere; and
(3) a venting valve interposed between the vent inlet port and the vent outlet port, wherein
the controller is configured to control the venting valve to permit venting of the dialysate holding tank.
18. The dialysis system of claim 16 , wherein the second group of flowpaths comprises a first dialysate flowpath and the fourth group of flowpaths comprises a first drain flowpath, wherein the first drain flowpath is fluidically connected to a first dialysate outlet port of the cassette, and the first dialysate flowpath comprises a first dialysate valve interposed between a first dialysate inlet port of the cassette and
(1) a second dialysate outlet port of the cassette configured to fluidically connect to the dialysate holding tank, and
(2) a second dialysate valve fluidically connected to the first drain flowpath, wherein
the controller is configured to control the first and second dialysate valves to direct the dialysate solution from the first dialysate inlet port to either the dialysate holding tank or the drain.
19. The dialysis system of claim 18 , wherein the third group of flowpaths comprises a second dialysate flowpath, the second dialysate flowpath comprising a first pneumatically actuated diaphragm pump interposed between a second dialysate inlet port of the cassette and the second dialysate outlet port of the cassette, wherein the controller is configured to control the pump to transfer the dialysate solution from the dialysate holding tank to the dialysate balancing circuit.
20. The dialysis system of claim 19 , further comprising a second pneumatically actuated diaphragm pump interposed between the second dialysate inlet port and the second dialysate outlet port, the second dialysate flowpath including a first pump inlet valve upstream of the first pump, a first pump outlet valve downstream of the first pump, a second pump inlet valve upstream of the second pump, and a second pump outlet valve downstream of the second pump, wherein the controller is configured to control the first and second pumps and the pump valves to pump dialysate solution with the first and second pumps either sequentially or simultaneously.
21. The dialysis system of claim 19 , wherein the fourth group of flowpaths comprises a second drain flowpath connecting a third dialysate inlet port of the cassette to the first dialysate outlet port, wherein the second drain flowpath comprises a third dialysate valve interposed between the third dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the third dialysate valve to direct the dialysate solution from an outlet of the balancing circuit to the drain.
22. The dialysis system of claim 21 , wherein the fourth group of flowpaths comprises a third drain flowpath connecting a fourth dialysate inlet port of the cassette to the first dialysate outlet port, wherein the third drain flowpath comprises a fourth dialysate valve interposed between the fourth dialysate inlet port and the first dialysate outlet port, and the controller is configured to control the fourth dialysate valve to direct dialysate from an inlet of the dialysate balancing circuit to the drain.
23. The dialysis system of claim 22 , wherein the second dialysate outlet port is configured for fluidic connection to a heater and an ultrafilter positioned upstream of the dialysate balancing circuit, the heater and ultrafilter being external to the cassette, and wherein the controller is configured to control the fourth dialysate valve to direct the dialysate solution from an outlet of the ultrafilter to the drain or to the dialysate holding tank.