IP Library Granted Patent US 10,613,171
Granted Patent B2
US 10,613,171 · App. 15/623,496 · Granted Apr 7, 2020

Multi-banded RF-pulse enhanced magnetization imaging

Inventors: Xiufeng Li (Shoreview, MN); Gregory J. Metzger (Lake Elmo, MN); Kamil Ugurbil (Minneapolis, MN); Dingxin Wang (Apple Valley, MN)
Assignees: Siemens Healthcare GmbH; Regents of the University of Minnesota
G01R33/4616G01R33/56G01R33/5605G01R33/4835
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Quick Facts
Patent No.
US 10,613,171
App. No.
15/623,496
Granted
Apr 7, 2020
Kind
B2
Abstract

Embodiments can provide a method for multi-banded RF-pulse enhanced magnetization imaging, the method comprising determining, by a processor, a frequency offset against a central frequency by specifying an offset frequency for one or more RF coils close to a frequency peak of mobile water; and simultaneously applying, by one or more RF coils, one or more bands of Gaussian RF pulses around the central frequency to a patient from a medical imaging device; wherein the one or more bands of Gaussian RF pulses are symmetrically applied having a distance from the central frequency equal to the frequency offset.

Claims (35)

1. A method for performing magnetization transfer preparation in a magnetization transfer imaging, the method comprising:

determining, by a processor, a first frequency offset against a central frequency of mobile water, wherein the central frequency is a frequency peak of the mobile water; and

simultaneously applying, by one or more RF coils, a plurality of multi-banded Gaussian RF pulses around the central frequency to a patient from a medical imaging device, wherein each multi-banded Gaussian RF pulse includes at least two RF pulse components, and each RF pulse component has a different frequency offset;

wherein the plurality of multi-banded Gaussian RF pulses are symmetrically applied, wherein a distance between a first RF pulse component of each multi-banded Gaussian RF pulse and the central frequency is equal to the first frequency offset, wherein the first RF pulse component is closest to the central frequency.

2. The method as recited in claim 1 , wherein each RF pulse component is designed with a different frequency selection.

3. The method as recited in claim 1 , further comprising:

modulating, by a radio-frequency system, a different amplitude of each RF pulse component prior to application to the patient.

4. The method as recited in claim 1 , further comprising:

combining the application of the plurality of multi-banded Gaussian RF pulses with an image acquisition method.

5. The method as recited in claim 1 , further comprising:

performing, by an image processor, a multi-banded and simultaneous multiple slice dual-echo GRE imaging readout.

6. A computer program product for performing magnetization transfer preparation in a magnetization transfer imaging, the non-transitory computer program product comprising a non-transitory computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to cause the processor to:

determine a first frequency offset against a central frequency of mobile water, wherein the central frequency is a frequency peak of the mobile water; and

simultaneously apply a plurality of multi-banded Gaussian RF pulses around the central frequency to a patient from a medical imaging device, wherein each multi-banded Gaussian RF pulse includes at least two RF pulse components, and each RF pulse component has a different frequency offset;

wherein the plurality of multi-banded Gaussian RF pulses are symmetrically applied, wherein a distance between a first RF pulse component of each multi-banded Gaussian RF pulse and the central frequency is equal to the first frequency offset, wherein the first RF pulse component is closest to the central frequency.

7. The computer program product as recited in claim 6 , wherein each RF pulse component is designed with a different frequency selection.

8. The computer program product as recited in claim 6 , wherein the processor is further caused to:

modulate a different amplitude of each RF pulse component prior to application to the patient.

9. The computer program product as recited in claim 6 , wherein the processor is further caused to:

combine the application of the plurality of multi-banded Gaussian RF pulses with an image acquisition method.

10. The computer program product as recited in claim 6 , wherein the processor is further caused to:

perform a multi-banded and simultaneous multiple slice dual-echo GRE imaging readout.

11. A system for simultaneous multi-slice pulse wave velocity measurement, the system comprising:

a medical imaging device comprising:

a magnetic field generator;

a gradient and shim coil control module; and

a radio-frequency system configured to:

determine a first frequency offset against a central frequency of mobile water, wherein the central frequency is a frequency peak of the mobile water;

simultaneously apply a plurality of multi-banded Gaussian RF pulses around the central frequency to a patient from a medical imaging device, wherein each multi-banded Gaussian RF pulse includes at least two RF pulse components, and each RF pulse component has a different frequency offset;

wherein the plurality of multi-banded Gaussian RF pulses are symmetrically applied, wherein a distance between a first RF pulse component of each multi-banded Gaussian RF pulse and the central frequency is equal to the first frequency offset, wherein the first RF pulse component is closest to the central frequency.

12. The system as recited in claim 11 , wherein each RF pulse component is designed with a different frequency selection.

13. The system as recited in claim 11 , wherein the radio-frequency system is further configured to:

modulate a different amplitude of each RF pulse component prior to application to the patient.

14. The system as recited in claim 11 , wherein the radio-frequency system is further configured to:

combine the application of the plurality of multi-banded Gaussian RF pulses with an image acquisition method.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066267/0346 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 19, 2020
From: UGURBIL, KAMIL
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 051852/0796 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2019
From: METZGER, GREGORY J.
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 049575/0678 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2019
From: LI, XIUFENG
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 047937/0199 →
CONFIRMATORY LICENSE Recorded Dec 4, 2017
From: UNIVERSITY OF MINNESOTA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 044666/0703 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2017
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 043332/0248 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2017
From: WANG, DINGXIN
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 043211/0747 →
Continuity (2)
Provisional Application 62471129 · Mar 14, 2017
Related Publication 20180267120A1 · Sep 20, 2018
Cited By (1)
US 12,433,502