IP Library Granted Patent US 10,898,620
Granted Patent B2
US 10,898,620 · App. 15/624,235 · Granted Jan 26, 2021

Composite stent having multi-axial flexibility and method of manufacture thereof

Inventors: Kamal Ramzipoor (Fremont, CA); Richard J. Saunders (Redwood City, CA)
Assignee: Razmodics LLC
A61L31/148A61F2/07A61F2/82A61L31/04A61L31/06A61L31/14A61L31/16B29C41/003B29C41/14A61F2/24A61F2002/30062A61F2002/30535A61F2210/0004A61F2210/0019A61F2240/004B29C49/00B29K2105/0035B29K2995/0056B29L2031/7532
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,898,620
App. No.
15/624,235
Granted
Jan 26, 2021
Kind
B2
Abstract

A bioabsorbable composite stent structure, comprising bioabsorbable polymeric ring structures which retain a molecular weight and mechanical strength of a starting substrate and one or more interconnecting struts which extend between and couple adjacent ring structures. The ring structures can have a formed first diameter and being radially compressible to a smaller second diameter and re-expandable to the first diameter. The ring structures can comprise a base polymeric layer. The interconnecting struts can be formed from a polymer blend or co-polymer of poly-L-lactide (PLLA) and an elastomeric polymer. The interconnecting struts each can have a width that is less than a circumference of one of the ring structures. The adjacent ring structures can be axially and rotationally movable relative to one another via the interconnecting struts. The interconnecting struts can also be bioabsorbable.

Claims (37)

1. A bioabsorbable composite stent structure, comprising:

bioabsorbable polymeric ring structures which retain a molecular weight and mechanical strength of a starting substrate, the ring structures having a formed first diameter and being radially compressible to a smaller second diameter and re-expandable to the first diameter, wherein the ring structures are separated from one another and comprise a base polymeric layer;

one or more interconnecting struts which extend between and couple adjacent ring structures, wherein the interconnecting struts each has a width which is less than a circumference of one of the ring structures,

wherein the interconnecting struts are formed from a polymer blend or co-polymer of poly-L-lactide (PLLA) and an elastomeric polymer,

wherein the adjacent ring structures are axially and rotationally movable relative to one another via the interconnecting struts, and

wherein the one or more interconnecting struts are bioabsorbable.

2. The stent structure of claim 1 , wherein the elastomeric polymer is polycaprolactone (PCL).

3. The stent structure of claim 2 , wherein the PCL is 1% to 10% of the polymer blend or co-polymer.

4. The stent structure of claim 2 , wherein the PCL is 1% to 50% of the polymer blend or co-polymer.

5. The stent structure of claim 1 , wherein the polymer blend or co-polymer has a glass transition temperature between 50° C. and 65° C.

6. The stent structure of claim 1 , wherein the ring structures are spaced closer to one another along a first portion than along a second portion of the stent structure.

7. The stent structure of claim 1 , wherein a terminal ring structure is relatively more flexible than a remainder of the ring structures.

8. The stent structure of claim 1 , wherein the base polymeric layer is a bioabsorbable polymeric substrate formed via a dip-coating process.

9. A bioabsorbable composite stent structure, comprising:

bioabsorbable polymeric ring structures which retain a molecular weight and mechanical strength of a starting substrate, the ring structures having a formed first diameter and being radially compressible to a smaller second diameter and re-expandable to the first diameter, wherein the ring structures are separated from one another and comprise a base polymeric layer;

a plurality of interconnecting struts which extend between and couple adjacent ring structures, wherein the interconnecting struts each has a width which is less than a circumference of one of the ring structures,

wherein the interconnecting struts are formed from a polymer blend or co-polymer of poly-L-lactide (PLLA) and an elastomeric polymer,

wherein the plurality of interconnecting struts are positioned along a length of the stent structure in a circumferentially alternating manner between immediately adjacent ring structures,

wherein the ring structures are spaced closer to one another along a first portion than along a second portion of the stent structure, and

wherein the one or more interconnecting struts are bioabsorbable.

10. The stent structure of claim 9 , wherein the elastomeric polymer is polycaprolactone (PCL).

11. The stent structure of claim 10 , wherein the PCL is 1% to 10% of the polymer blend or co-polymer.

12. The stent structure of claim 10 , wherein the PCL is 1% to 50% of the polymer blend or co-polymer.

13. The stent structure of claim 9 , wherein the polymer blend or co-polymer has a glass transition temperature between 50° C. and 65° C.

14. The stent structure of claim 9 , wherein the base polymeric layer is a bioabsorbable polymeric substrate formed via a dip-coating process.

15. A bioabsorbable composite stent structure, comprising:

bioabsorbable polymeric ring structures which retain a molecular weight and mechanical strength of a starting substrate, the ring structures having a formed first diameter and being radially compressible to a smaller second diameter and re-expandable to the first diameter, wherein the ring structures are separated from one another and comprise a base polymeric layer;

one or more interconnecting struts which extend between and couple adjacent ring structures, wherein the interconnecting struts each has a width which is less than a circumference of one of the ring structures,

wherein the interconnecting struts are formed from a polymer blend or co-polymer of poly-L-lactide (PLLA) and an elastomeric polymer,

wherein the one or more interconnecting struts is more elastic than the ring structures,

wherein a terminal ring structure is relatively more flexible than a remainder of the ring structures, and

wherein the one or more interconnecting struts are bioabsorbable.

16. The stent structure of claim 15 , wherein the elastomeric polymer is polycaprolactone (PCL).

17. The stent structure of claim 16 , wherein the PCL is 1% to 10% of the polymer blend or co-polymer.

18. The stent structure of claim 16 , wherein the PCL is 1% to 50% of the polymer blend or co-polymer.

19. The stent structure of claim 15 , wherein the polymer blend or co-polymer has a glass transition temperature between 50° C. and 65° C.

20. The stent structure of claim 15 , wherein the base polymeric layer is a bioabsorbable polymeric substrate formed via a dip-coating process.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2020
From: AMARANTH MEDICAL PTE. LTD.
To: AMTH LIQUIDATING TRUST
Reel/Frame 052766/0298 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2020
From: AMTH LIQUIDATING TRUST
To: RAZAVI, MAHMOOD
Reel/Frame 052766/0362 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2020
From: RAZAVI, MAHMOOD
To: RAZMODICS LLC
Reel/Frame 052766/0463 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 23, 2017
From: RAMZIPOOR, KAMAL; SAUNDERS, RICHARD J.
To: AMARANTH MEDICAL PTE.
Reel/Frame 043927/0134 →
Continuity (7)
Continuation In Part 15439002 · Feb 22, 2017
Continuation 13476853 · May 21, 2012
Division 12143659 · Jun 20, 2008
Division 15624235 · Jun 15, 2017
Continuation In Part 12541095 · Aug 13, 2009
Provisional Application 61088433 · Aug 13, 2008
Related Publication 20170281832A1 · Oct 5, 2017