VEGFC production promoter
The purpose of this invention is to find a novel fragrance component effective for prevention or control of swelling, lymphedema, skin aging or obesity from the viewpoint of activation of lymph vessel function by promotion of the expression of VEGFC. This invention provides a swelling improving agent, lymph vessel activator and VEGFC production promoter characterized by containing one or a plurality of components selected from the group consisting of rose oxide, citronellyl acetate and niaouli oil.
1. A method of promoting VEGFC production comprising administering a formulation comprising 0.0001 to 0.1% by weight of citronellyl acetate, wherein swelling is ameliorated via the promotion of VEGFC production.
2. The method according to claim 1 , wherein lymphangiogenesis and/or lymphatic function are promoted via the promotion of VEGFC production.
3. The method according to claim 1 , wherein the formulation comprises 0.001 to 0.01% by weight of citronellyl acetate.
4. The method according to claim 1 , wherein the formulation comprises 0.005 to 0.01% by weight of citronellyl acetate.
5. A method of promoting VEGFC production comprising administering a formulation comprising 0.0001 to 0.1% by weight of citronellyl acetate, wherein lymphedema is ameliorated via the promotion of VEGFC production.