Composite joint arthroplasty systems and methods
A prosthesis may have an articulating component formed via casting and a 3D printed bone anchoring component with a joint-facing side and a bone-facing side. The bone-facing side may have a bone engagement surface with a porous structure with pores selected to facilitate in-growth of the bone into the pores. The bone facing side may further have a surface layer of Titanium Dioxide nanotubes. The joint-facing side may be secured to the articulating component by melting Titanium nanoparticles at a temperature below the melting temperatures of the major constituents of the articulating component and/or the bone anchoring component, such as Cobalt, Chromium, and/or Titanium, so as to avoid significantly modifying the crystalline structures of the articulating component and/or the bone anchoring component. The melting temperature of the Titanium nanoparticles may be about 500° C.
1. A method for manufacturing a prosthesis for replacing an articular surface on a bone, the method comprising:
casting an articulating component comprising:
an articulating component joint-facing side comprising an articular surface; and
an articulating component bone-facing side comprising a bone-facing shape; and
fabricating a bone anchoring component with a porous structure, comprising:
a bone anchoring component joint-facing side comprising a joint-facing shape that is complementary to the bone-facing shape; and
a bone anchoring component bone-facing side comprising a bone engagement surface having a porous structure with pores selected to facilitate in-growth of the bone into the pores; and
securing the bone anchoring component joint-facing side to the articulating component bone-facing side by:
applying Titanium-based nanoparticles between the articulating component bone-facing side and the bone anchoring component joint-facing side; and
heating the Titanium-based nanoparticles to a temperature sufficient to melt the Titanium-based nanoparticles, but insufficient to melt the articulating component or bone anchoring component.
2. The method of claim 1 , wherein fabricating the bone anchoring component comprises direct metal laser sintering Titanium to form a porous structure.
3. The method of claim 1 , further comprising anodizing the bone anchoring component to form a surface layer of Titanium Dioxide nanotubes on the bone anchoring component joint-facing side.
4. The method of claim 3 , further comprising heating the bone anchoring component to a temperature sufficient to change at least a portion of the surface layer of Titanium Dioxide nanotubes to anatase.
5. The method of claim 1 , wherein:
casting the articulating component comprises casting the articulating component from an alloy of Cobalt Chromium to establish one or more crystalline structures of the alloy of Cobalt Chromium; and
heating the Titanium-based nanoparticles to the temperature comprises heating at least part of the bone anchoring component and at least part of the articulating component to a bonding temperature below melting temperatures of Cobalt and Chromium, so as to leave the crystalline structures intact.
6. The method of claim 5 , wherein heating the Titanium-based nanoparticles comprises:
placing the articulating component, the bone anchoring component, and the Titanium-based nanoparticles in a furnace; and
in the furnace, heating the articulating component, the bone anchoring component, and the Titanium-based nanoparticles to the temperature.
7. The method of claim 5 , wherein heating at least part of the bone anchoring component and part of the articulating component to the bonding temperature comprises laser welding a perimeter and/or seams of the bone anchoring component joint-facing side and the articulating component bone-facing side together.
8. The method of claim 5 , further comprising, prior to heating at least part of the bone anchoring component and part of the articulating component to the bonding temperature, applying a paste to one or both of the bone anchoring component joint-facing side and the articulating component bone-facing side, the paste comprising the Titanium-based nanoparticles and a gelatin and/or a glycerin.
9. The method of claim 8 , further comprising, after applying the paste on one or both of the bone anchoring component joint-facing side and the articulating component bone-facing side, and prior to heating at least the bone anchoring component joint-facing side and the articulating component bone-facing side to the bonding temperature:
assembling the articulating component and the bone anchoring component such that the paste is sandwiched between the bone anchoring component joint-facing side and the articulating component bone-facing side; and
pressing the bone anchoring component joint-facing side and the articulating component bone-facing side together.
10. The method of claim 9 , wherein heating at least the bone anchoring component joint-facing side and the articulating component bone-facing side to the bonding temperature comprises, with the bone anchoring component joint-facing side and the articulating component bone-facing side pressed together, heating at least the bone anchoring component joint-facing side and the articulating component bone-facing side to 500° C. to debind the gelatin and/or glycerin and melt the Titanium-based nanoparticles.
11. A method for manufacturing a prosthesis for replacing an articular surface on a bone, the method comprising:
casting metals comprising at least Cobalt and Chromium to form an articulating component comprising:
an articulating component joint-facing side comprising an articular surface; and
an articulating component bone-facing side comprising a bone-facing shape; and
direct metal laser sintering Titanium to form a bone anchoring component comprising:
a bone anchoring component joint-facing side comprising a joint-facing shape that is complementary to the bone-facing shape; and
a bone anchoring component bone-facing side comprising a bone engagement surface having a porous structure with pores selected to facilitate in-growth of the bone into the pores;
applying a paste containing flake-shaped Titanium-based nanoparticles produced via ball milling to at least one of the bone anchoring component joint-facing side and the articulating component bone-facing side;
assembling the articulating component and the bone anchoring component such that the paste is sandwiched between the bone anchoring component joint-facing side and the articulating component bone-facing side; and
heating the paste to a bonding temperature sufficient to commence melting of the Titanium-based nanoparticles to secure the bone anchoring component joint-facing side to the articulating component bone-facing side.
12. The method of claim 11 , further comprising:
anodizing the bone anchoring component to form a surface layer of Titanium Dioxide nanotubes on the bone anchoring component joint-facing side; and
after assembling the articulating component and the bone anchoring component, pressing the articulating component and the bone anchoring component together;
wherein:
the paste further comprises a gelatin and/or a glycerin; and
heating the paste to the bonding temperature comprises, with the articulating component and the bone anchoring component pressed together, heating at least the bone anchoring component joint-facing side and the articulating component to a temperature sufficient to debind the gelatin and/or glycerin, melt the Titanium-based nanoparticles, and changing at least a portion of the surface layer of Titanium Dioxide nanotubes to anatase.