IP Library Granted Patent US 10,137,070
Granted Patent B2
US 10,137,070 · App. 15/629,517 · Granted Nov 27, 2018

Composition including ionone or salt thereof as active ingredient and having effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging

Inventor: Tae Sun Park (Seoul, KR)
Assignee: YONSEI UNIVERSITY TECHNOLOGY HOLDINGS, INC.
A61K8/35A23L33/10A61K8/676A61Q19/007A61Q19/08A23V2002/00A61K2800/28
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Quick Facts
Patent No.
US 10,137,070
App. No.
15/629,517
Granted
Nov 27, 2018
Kind
B2
Abstract

Provided herein are a cosmetic composition, a health functional food composition, a pharmaceutical composition, and a quasi-drug composition that include ionone or a salt thereof as an active ingredient and have an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging. The ionone or the salt thereof has an activity of enhancing skin moisture content, reducing skin moisture evaporation, increasing procollagen secretion, promoting collagen biosynthesis, suppressing collagen fiber damage, suppressing collagen fiber decomposition, inhibiting erythema, and suppressing the thickening of a skin epidermis layer, and thus may be usefully used as a material of functional cosmetics, health functional foods, pharmaceuticals, quasi-drugs, or the like that provide an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, and/or alleviating skin photoaging.

Claims (9)

1. A method of enhancing skin moisturizing, exfoliating skin,

improving skin elasticity, inhibiting erythema, improving skin wrinkles, and/or alleviating skin photoaging, the method comprising administering or taking a composition comprising:

a skin active ingredient consisting of ionone or a pharmaceutically acceptable or consisting of ionone or a pharmaceutically acceptable salt thereof and vitamin C; and

a carrier,

wherein the composition i) increases the level of PIP(procollagen type I C-peptide), ii) increases the expression level of Collagen Type 1α1, 1α2, 3α1, or iii) decreases the expression level of MMP-1a, MMP-3, and MMP-9.

2. The method according to claim 1 , wherein the composition is cosmetic composition, health functional food composition, pharmaceutical or quasi-drug composition.

3. The method according to claim 2 , wherein the cosmetic composition is prepared in any one formulation selected from the group consisting of a skin lotion, a skin softener, a skin toner, an astringent, a lotion, a milk lotion, a moisturizing lotion, a nutrition lotion, a massage cream, a nutrition cream, a moisturizing cream, a hand cream, an essence, a pack, a mask pack, a mask sheet, an exfoliating agent, a soap, a shampoo, a cleansing foam, a cleansing lotion, a cleansing cream, a body lotion, a body cleanser, an emulsion, a press powder, a loose powder, and an eye shadow.

4. The method according to claim 2 , wherein the health functional food composition is prepared in any one formulation selected from the group consisting of tablets, granules, powder, capsules, a liquid solution, and pills.

5. The method according to claim 1 , wherein an amount of the ionone or the pharmaceutically acceptable salt thereof ranges from about 0.0001 wt % to about 20 wt % with respect to a total weight of the composition.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2018
From: YONSEI UNIVERSITY TECHNOLOGY HOLDINGS, INC.
To: BOTANICSENS
Reel/Frame 047744/0356 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2018
From: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
To: YONSEI UNIVERSITY TECHNOLOGY HOLDINGS, INC.
Reel/Frame 046547/0322 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2017
From: PARK, TAE SUN
To: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Reel/Frame 042983/0756 →
Priority Claims (1)
KR 10-2016-0077927 · Jun 22, 2016 · national
Continuity (1)
Related Publication 20170367954A1 · Dec 28, 2017
Cited By (1)
US 12,521,335