IP Library Granted Patent US 10,316,088
Granted Patent B2
US 10,316,088 · App. 15/636,590 · Granted Jun 11, 2019

Heterodimeric antibodies that bind somatostatin receptor 2

Inventors: Gregory Moore (Azusa, CA); Rumana Rashid (Temple City, CA); Sung-Hyung Lee (San Gabriel, CA); Paul Foster (Rancho Sante Fe, CA)
Assignee: Xencor, Inc.
C07K16/2809A61P35/00C07K16/2869A61K2039/505C07K2317/31C07K2317/52C07K2317/53C07K2317/55C07K2317/56C07K2317/622C07K2317/64C07K2317/73
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Quick Facts
Patent No.
US 10,316,088
App. No.
15/636,590
Granted
Jun 11, 2019
Kind
B2
Abstract

The present invention is directed to antibodies, including novel antigen binding domains and heterodimeric antibodies, that bind somatostatin receptor 2 (SSTR2).

Claims (13)

1. A heterodimeric antibody comprising:

a) a first heavy chain comprising the amino acid sequence of SEQ ID NO: 1080;

b) a second heavy chain comprising the amino acid sequence of SEQ ID NO: 1070; and

c) a light chain comprising the amino acid sequence of SEQ ID NO: 1075.

2. A nucleic acid composition comprising:

a) a first nucleic acid encoding said first heavy chain of claim 1 ;

b) a second nucleic acid encoding said second heavy chain of claim 1 ; and

c) a third nucleic acid encoding said light chain of claim 1 .

3. An expression vector composition comprising:

a) a first expression vector comprising said first nucleic acid of claim 2 ;

b) a second expression vector comprising said second nucleic acid of claim 2 ; and

c) a third expression vector comprising said third nucleic acid of claim 2 .

4. A host cell comprising said expression vector composition of claim 3 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2019
From: MOORE, GREGORY; RASHID, RUMANA; LEE, SUNG-HYUNG; FOSTER, PAUL
To: XENCOR, INC.
Reel/Frame 047994/0156 →
Continuity (5)
Provisional Application 62355820 · Jun 28, 2016
Provisional Application 62355821 · Jun 28, 2016
Provisional Application 62397322 · Sep 20, 2016
Provisional Application 62481065 · Apr 3, 2017
Related Publication 20180118827A1 · May 3, 2018
Cited By (9)
US 12,359,002 US 12,398,207 US 12,404,329 US 12,415,849 US 12,466,897 US 12,617,872 US 12,655,230 US 12,662,553 US 12,698,341