Seal element for anastomosis
A seal element for sealing between tissue lumens includes a first material for allowing tissue ingrowth and a second sealant material.
1. A seal element for positioning adjacent tubular sections of tissue to be joined in an anastomosis, the seal element comprising:
a first material that promotes tissue ingrowth, the first material being selected from the group consisting of a foam, a mesh, a non-woven structure, a perforated sheet and combinations thereof; and
a second material comprising a sealant at least partially surrounding the first material, the second material being compressible, the seal element being circular and having a centrally located aperture, the first material being disposed inwardly of the second material and the second material configured to engage the tissue to provide a seal, at least one of the first or second materials further comprising at least one medically useful substance, the at least one medically useful substance comprising a chemotherapeutic.
2. The seal element of claim 1 , wherein the first material is a porous material.
3. The seal element of claim 1 , wherein the first material is selected from the group consisting of glycolide, lactide, caprolactone, trimethylene carbonate, dioxanone, polyalkylene oxides, and combinations thereof.
4. The seal element of claim 1 , wherein the first material comprises a porous material having pores ranging in size from about 50 μm to about 200 μm.
5. The seal element of claim 1 , wherein the first material has a thickness ranging from about 0.010 inches to about 0.020 inches.
6. The seal element of claim 1 , wherein the second material is expandable.
7. The seal element of claim 1 , wherein the second material is a hydrophilic material.
8. The seal element of claim 1 , wherein the second material is derived from a monomer selected from the group consisting of methacrylic acid, acrylic acid, n-vinyl pyrrolidone, potassium sulfopropyl acrylate, potassium sulfopropyl methacrylate, acrylamide, dimethylacrylamide, 2-methacryloyloxyethyl phosphorylcholine, hydroxethylmethacrylate, 2-hydroxyethyl methacrylate and combinations thereof.
9. The seal element of claim 1 , wherein the second material comprises a surface having a pattern formed thereon.
10. A circular stapling instrument having an anvil and a staple cartridge, the staple cartridge defining two circular rows of surgical staples, and the seal element according to claim 1 mounted thereon.