IP Library › Granted Patent US 10,470,837
Granted Patent B2
US 10,470,837 · App. 15/682,804 · Granted Nov 12, 2019

Apparatus and method for treating rhinitis

Inventors: Bryant Lin (Menlo Park, CA); David Moosavi (Redwood City, CA); Mojgan Saadat (Atherton, CA); Vahid Saadat (Atherton, CA)
Assignee: Arrinex, Inc.
A61B90/06A61B18/02A61B18/082A61B18/1485A61B18/22A61B34/20A61B90/30A61B90/37A61N7/02A61B18/1815A61B2017/00075A61B2017/00106A61B2018/00327A61B2018/00434A61B2018/00577A61B2018/00863A61B2018/00982A61B2018/207A61B2018/2211A61B2034/2046A61B2034/2055A61B2090/306A61B2090/363A61B2090/3612A61B2090/3614A61B2090/3945
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Quick Facts
Patent No.
US 10,470,837
App. No.
15/682,804
Granted
Nov 12, 2019
Kind
B2
Abstract

Devices and methods for treating rhinitis are described where the devices are configured to ablate a single nerve branch or multiple nerve branches of the posterior nasal nerves located within the nasal cavity. A surgical probe may be inserted into the sub-mucosal space of a lateral nasal wall and advanced towards a posterior nasal nerve associated with a middle nasal turbinate or an inferior nasal turbinate into a position proximate to the posterior nasal nerve where neuroablation of the posterior nasal nerve may be performed with the surgical probe. The probe device may utilize a visible light beacon that provides trans-illumination of the sub-mucosal tissue or an expandable structure disposed in the vicinity of the distal end of the probe shaft to enable the surgeon to visualize the sub-mucosal position of the distal end of the surgical probe from inside the nasal cavity using, e.g., an endoscope.

Claims (14)

1. A method for treating rhinitis of a patient, the method comprising:

advancing a distal end of a surgical probe within a lateral nasal wall tissue of a nasal cavity of a patient and towards at least one nasal nerve associated with the lateral nasal wall tissue, the surgical probe comprising a surgical probe shaft with a proximal end and the distal end, a handle coupled to the proximal end, and a cryo-ablation element disposed on the distal end;

sensing arterial or venous blood flow within the lateral nasal wall to identify an artery or vein associated with the at least one nasal nerve; and

cryogenically ablating the at least one nasal nerve with the cryo-ablation element to reduce at least one symptom of rhinitis while avoiding damage to the identified artery or vein associated with the at least one nasal nerve.

2. The method of claim 1 , wherein the at least one nasal nerve comprises a posterior nasal nerve or branches thereof and the artery or vein associated with the at least one nasal nerve comprises a sphenopalatine artery or vein.

3. The method of claim 1 , wherein sensing arterial or venous blood flow is carried out prior to cryogenically ablating the at least one nasal nerve.

4. The method of claim 1 , wherein sensing is carried out a by ultrasonic or optical sensor.

5. The method of claim 1 , further comprising bluntly dissecting with the distal end of a surgical probe along a surgical plane into a sub-mucosal space of the lateral nasal wall.

6. The method of claim 5 , wherein the surgical plane is defined by a bone of the lateral nasal wall and overlying nasal mucosa and bluntly dissecting comprises inserting the distal end of the surgical probe shaft into the sub-mucosal space at a position proximate of the at least one nasal nerve along the surgical plane.

7. The method of claim 5 , further comprising visually tracking a position of the distal end of the surgical probe shaft with a position indicator while advancing the distal end of the surgical probe shaft within the lateral nasal wall tissue.

8. The method of claim 7 , wherein the position indicator comprises an optical beacon, and wherein visually tracking the position of the distal end of the surgical probe shaft comprises trans-illuminating the optical beacon through mucosa.

9. The method of claim 7 , wherein the position indicator comprises an expandable structure, and wherein visually tracking the position of the distal end of the surgical probe shaft comprises expanding the expandable structure so as to displace mucosal tissue overlying the distal end of the surgical probe shaft.

10. The method of claim 1 , wherein cryogenically ablating the at least one nasal nerve comprises delivering a cryogenic fluid into the cryo-ablation element from a cryogenic fluid source fluidly coupled to the cryo-ablation element.

11. The method of claim 10 , wherein the cryo-ablation element comprises an expandable structure, wherein the expandable structure is configured to transition from a deflated configuration to an inflated configuration upon evaporation of the cryogenic fluid within the expandable structure.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2026
From: ARRINEX, INC,
To: STRYKER CORPORATION
Reel/Frame 076101/0884 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2018
From: LIN, BRYANT; MOOSAVI, DAVID; SAADAT, MOJGAN; SAADAT, VAHID
To: NIDUS MEDICAL LLC
Reel/Frame 045977/0112 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2018
From: NIDUS MEDICAL LLC
To: ARRINEX, INC.
Reel/Frame 045977/0325 →
Continuity (3)
Continuation 14808690 · Jul 24, 2015
Provisional Application 62028995 · Jul 25, 2014
Related Publication 20180078327A1 · Mar 22, 2018
Cited By (7)
US 12,318,138 US 12,357,817 US 12,408,974 US 12,478,806 US 12,539,167 US 12,611,375 US 12,697,247