IP Library Granted Patent US 9,951,227
Granted Patent B2
US 9,951,227 · App. 15/698,069 · Granted Apr 24, 2018

Monoazo dyes with cyclic amine as fluorescence quenchers

Inventors: Zaiguo Li (Little Neck, NY); Praveen Pande (Holbrook, NY); Natarajan Raju (Kendall Park, NY)
Assignee: Enzo Biochem, Inc.
C09B29/3643C09B56/005C12Q1/68C12Q1/6818C12Q1/6846C12Q1/6876C12Q1/708C12Q2565/101
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Quick Facts
Patent No.
US 9,951,227
App. No.
15/698,069
Granted
Apr 24, 2018
Kind
B2
Abstract

The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.

Claims (1)

1. A compound selected from the up consisting of

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jul 24, 2023
From: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
To: ENZO BIOCHEM, INC.; ENZO CLINICAL LABS, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP; ENZO LIFE SCIENCES, INC.
Reel/Frame 064369/0031 →
SECURITY INTEREST Recorded Apr 3, 2023
From: ENZO LIFE SCIENCES, INC.; ENZO CLINICAL LABS, INC.; ENZO BIOCHEM, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP
To: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
Reel/Frame 063239/0103 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2017
From: LI, ZAIGUO; PANDE, PRAVEEN; RAJU, NATARAJAN
To: ENZO BIOCHEM, INC.
Reel/Frame 044117/0828 →
Continuity (2)
Division 14672944 · Mar 30, 2015
Related Publication 20170369954A1 · Dec 28, 2017