Antimicrobial coatings capable of reducing the number of murine norovirus inoculated thereon
The present disclosure provides antimicrobial coatings on a surface comprising a reactive silanol and triethanolamine. In various examples the reactive silane is 3-chloropropylsilane triol. The coating is capable of reducing the number of Murine norovirus and E. Coli inoculated on the dried coating. In various examples, the coating further comprises a mixture of peroxotitanium acid and peroxo-modified anatase sol. The compositions may be electrostatically sprayed on the surface, and in certain examples, a mixture of silanol and triethanolamine is spray-coated on the surface followed by an aqueous mixture of peroxotitanium acid and peroxo-modified anatase sol.
1. An antimicrobial coating on a surface of a substrate, the coating comprising triethanolamine, a mixture of peroxotitanium acid and peroxo-modified anatase sol, and a silane having structure VI:
2. The antimicrobial coating of claim 1 , wherein the substrate is paper and melamine resin laminate.
3. The antimicrobial coating of claim 2 , wherein the antimicrobial coating exhibits ≥1.50 log viral count reduction in Murine norovirus 4 hours after initial inoculation of the coating with Murine norovirus.
4. The antimicrobial coating of claim 1 , wherein the substrate is stainless steel.
5. The antimicrobial coating of claim 4 , wherein the antimicrobial coating exhibits about a 2.3 log viral count reduction in Murine norovirus 4 hours after initial inoculation of the coating with Murine norovirus.
6. The antimicrobial coating of claim 4 , wherein the antimicrobial coating exhibits about a 2.58 log viral count reduction in Murine norovirus 6 hours after initial inoculation of the coating with Murine norovirus.
7. A method of coating a surface of a substrate with the antimicrobial coating of claim 1 , which method comprises:
(a) spray-coating on the surface a methanolic composition comprising triethanolamine and a silane having structure VI:
(b) allowing the methanolic composition to dry;
(c) spray-coating on the surface an aqueous composition of peroxotitanium acid and peroxo-modified anatase sol; and
(d) allowing the aqueous composition to dry, forming the antimicrobial coating.
8. The method of claim 7 , wherein the substrate is stainless steel.
9. The method of claim 8 , wherein the spray-coating of both the methanolic composition and the aqueous composition comprise electrostatic spraying.
10. The method of claim 9 , wherein the antimicrobial coating exhibits about a 5.33 log reduction in E. Coli 1 hour after initial inoculation of the coating with E. Coli.
11. The method of claim 9 , wherein the antimicrobial coating exhibits about a 6.71 log reduction in E. Coli 4 hours after initial inoculation of the coating with E. Coli.
12. The method of claim 8 , wherein neither the spray-coating of the methanolic composition nor the spray-coating of the aqueous composition comprises electrostatic spraying.
13. The method of claim 12 , wherein the antimicrobial coating exhibits about a 0.47 log reduction in E. Coli 1 hour after initial inoculation of the coating with E. Coli.
14. The method of claim 12 , wherein the antimicrobial coating exhibits about a 5.92 log reduction in E. Coli 4 hours after initial inoculation of the coating with E. Coli.
15. The method of claim 7 , wherein allowing the methanolic composition to dry comprises allowing at least 90 weight percent of the methanol to evaporate from the surface.
16. The method of claim 7 , wherein allowing the aqueous composition to dry comprises allowing at least 90 weight percent of the water to evaporate from the surface.