IP Library Granted Patent US 10,532,032
Granted Patent B2
US 10,532,032 · App. 15/728,799 · Granted Jan 14, 2020

Rolled collagen carrier

Inventors: Wolfgang Schoenhofer (St. Poelten, AT); Pernille Dybendal Pedersen (Frederiksberg, DK); Poul Bertelsen (Roskilde, DK); Henrik Braender (Kalundborg, DK); Ingrid Blanka (Hellmonsoedt, AT); Henrik Neuschaefer Larsen (Soborg, DK)
Assignee: TAKEDA AS
A61K9/7007A61F13/0276A61K38/363A61K38/4833A61K47/42A61L24/043A61L31/041A61B17/0057
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Quick Facts
Patent No.
US 10,532,032
App. No.
15/728,799
Granted
Jan 14, 2020
Kind
B2
Abstract

The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

Claims (20)

1. A method of treating a patient comprising administering to a patient in need thereof a form-stable coiled hemostatic collagen carrier

comprising a collagen sponge with a coating layer on the top surface of the collagen sponge, the coating layer comprising thrombin and fibrinogen, and

having the shape of an elongate element with a number of windings of the collagen carrier about the longitudinal axis of the elongate element and at least one outer winding(s),

wherein

the at least one outer winding(s) are orientated so that the coating layer constitutes the outer surface of each outer winding,

and wherein

the coiled collagen carrier is form-stable and defines a collagen carrier in a coiled configuration where said at least one outer winding(s) proceed along a spiral in a cross section of the collagen carrier.

2. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of surgery.

3. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of treating an injury associated with performing minimally invasive surgery in a patient.

4. The method of claim 3 , wherein leakage of cerebrospinal fluid or air/gas is present at the injury.

5. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing or treating an injury associated with performing endoscopic surgery in a patient.

6. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing injury to or treating a tissue in need of sealing and/or glueing.

7. The method of claim 6 , wherein the tissue is selected from brain, spinal cord, nerves, and nerve tissue.

8. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of improving or providing hemostasis in a patient.

9. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of promoting tissue sealing in a patient.

10. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of providing suture support in a patient.

11. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing or treating an injury associated with performing laparoscopic surgery in a patient.

12. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing or treating an injury associated with performing thoracoscopic surgery in a patient.

13. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing or treating post-surgical tissue adhesions in a patient.

14. The method of treating a patient according to claim 1 , wherein the method of treatment further comprises a method of preventing or treating bleeding in a patient's tissue in need of hemostasis.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2021
From: TAKEDA AS
To: TOPAZ INVESTMENT AS
Reel/Frame 057936/0082 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2017
From: SCHOENHOFER, WOLFGANG; BLANKA, INGRID; BERTELSEN, POUL; BRAENDER, HENRIK; LARSEN, HENRIK NEUSCHAEFER; PEDERSEN, PERNILLE
To: TAKEDA AS
Reel/Frame 044435/0017 →
Priority Claims (1)
EP 11167379 · May 24, 2011 · regional
Continuity (2)
Division 14117882
Related Publication 20180085322A1 · Mar 29, 2018