Alloy member usable in organisms and production method therefor
Provided are an alloy member which is usable in organisms, makes use of features of bio-affinity and biodegradability of magnesium, and is able to realize required duration of biodegradability, and a production method therefor. According to the present invention, the alloy member usable in organisms includes a base body that contains a magnesium alloy, a first protective layer that contains an oxide derived from a component of the base body or a complex of an oxide and a hydroxide derived from a component of the base body, and a second protective layer that contains a hydroxide derived from a component of the base body.
1. An alloy member usable in organisms, comprising:
a base body that contains a magnesium alloy of magnesium and a mixture containing Nd, Y, Mn, Zn and Zr;
a first protective layer that contains a complex of oxides of magnesium and Mn; and
a second protective layer that contains a complex of hydroxides of magnesium, Nd, Zn, Mn and Y.
2. The alloy member usable in organisms according to claim 1 ,
wherein the first protective layer is on a surface of the base body, and
wherein the second protective layer is on a surface of the first protective layer.
3. The alloy member usable in organisms according to claim 1 ,
wherein the base body contains Nd ranging from 0.5 to 5.0 percent by weight, Y ranging from 0.1 to 5.0 percent by weight, Mn ranging from 0.1 to 1.0 percent by weight, Zn ranging from 0.1 to 4.0 percent by weight, and Zr ranging from 0.1 to 1.0 percent by weight.
4. The alloy member usable in organisms according to claim 1 ,
wherein the alloy member is used in at least one of an artificial blood vessel, a stent, a suturing material for organisms, a vascular embolic coil, a clip, an encapsulant, a binding material for organisms, a binding material for bones, a mesh sheet, a correction material for bones, a solid or porous support material for bones, and a scaffold in which cells are retained and proliferate inside an organism.
5. A bio-implantation device, comprising
a structural member comprised of the alloy member usable in organisms according to claim 1 ,
wherein the bio-implantation device is biodegradable.
6. A production method for an alloy member usable in organisms, comprising:
a step of preparing a base body that contains a magnesium alloy of magnesium and a mixture containing Nd, Y, Mn, Zn and Zr;
a step of forming a first protective layer, which contains a complex of oxides of magnesium and Mn; and
a step of forming a second protective layer, which contains a complex of hydroxides of magnesium, Nd, Zn, Mn and Y, on the first protective layer.
7. An alloy member usable in organisms, comprising:
a base body that contains a magnesium alloy of magnesium and a mixture containing Nd, Gd and Zr;
a first protective layer that contains a complex of oxides of magnesium, Mn and Gd; and
a second protective layer that contains a complex of hydroxides of magnesium, Nd and Gd.
8. The alloy member usable in organisms according to claim 7 ,
wherein the base body contains Nd ranging from 0.5 to 5.0 percent by weight, Gd ranging from 0.1 to 5.0 percent by weight, and Zr ranging from 0.1 to 1.0 percent by weight.
9. A production method for an alloy member usable in organisms, comprising:
a step of preparing a base body that contains a magnesium alloy of magnesium and a mixture containing Nd, Gd and Zr;
a step of forming a first protective layer, which contains a complex of oxides of magnesium, Mn and Gd; and
a step of forming a second protective layer, which contains a complex of hydroxides of magnesium, Nd and Gd, on the first protective layer.