Capsule with volume-adjustable internal diaphragm

1. A multi-compartment capsule comprising:

a body;

a diaphragm, having two sidewalls and a bottom, extending into the body and defining a first compartment between an outer surface of the diaphragm and an inner surface of the body; and

a cap mounted to an outer surface of the body and opposed to the diaphragm, and defining a second compartment between an inner surface of the diaphragm and the cap;

wherein the two sidewalls of the diaphragm extend along and contact the inner surface of the body and are aligned with an open end of the body, forming a seal between the diaphragm and the body;

wherein the first compartment is configured to have a volume of about 423 mm 3 to about 743 mm 3 and contains a first ingredient;

wherein the second compartment is configured to have a volume of about 176 mm 3 to about 497 mm 3 and contains a second ingredient;

wherein the multi-compartment capsule has a total volume of about 910 mm 3 to about 950 mm 3 , containing the first compartment and the second compartment therein; and

wherein the multi-compartment capsule is configured to co-administer the first ingredient and the second ingredient during digestion.

2. The capsule of claim 1 , wherein the volume ratio of the first compartment to the second compartment is about 0.84 to about 4.2.

3. The capsule of claim 1 , wherein the length of the second compartment is about 5 mm to about 11.75 mm.

4. The capsule of claim 1 , wherein the length of the second compartment is less than 7 mm.

5. The capsule of claim 1 , wherein the length of the second compartment is greater than 10 mm.

6. The capsule of claim 1 , wherein the length of the first compartment is about 8 mm to about 25 mm.

7. The capsule of claim 1 , wherein the capsule is about 23.5 mm in length.

8. The capsule of claim 1 , wherein the length of contact between a sidewall of the diaphragm and a sidewall of the body is about 0.91 mm to about 8.5 mm.

9. The capsule of claim 1 , wherein the bottom of the diaphragm has a shape selected from the group consisting of curved and flattened.

10. The capsule of claim 1 , wherein the first ingredient and the second ingredient are each volume-critical.

11. The capsule of claim 1 , wherein the first compartment has a sufficient volume to administer a therapeutically effective dose of the first ingredient, and wherein the second compartment has a sufficient volume to administer a therapeutically effective dose of the second ingredient.

12. The capsule of claim 1 , wherein the second ingredient is aspirin in an amount of about 10 mg to about 800 mg and the first ingredient is an oil in an amount of about 10 mg to about 700 mg.

13. The capsule of claim 1 , wherein the first ingredient is an oil selected from the group consisting of omega-3 oil, red palm oil, fish oil, hill oil, walnut oil, saw palmetto oil, castor oil, garlic oil, flaxseed oil, canola oil, soybean oil, cannabis oil, argan oil, coconut oil, peppermint oil, evening primrose oil, oregano oil, emu oil, cod liver oil, algae oil, grape seed oil, rose oil, clove oil, vitamin E oil, blueberry seed oil, raspberry seed oil, pumpkin seed oil, hemp oil, alpha linolenic acid, conjugated linoleic acid, docosahexaenoic acid, ginger oil, lavender oil, and combinations thereof.

14. The capsule of claim 1 , wherein the second ingredient is selected from the group consisting of alpha-carotene, beta-carotene, biotin, cadmium, caffeine, calcium, cinnamon, copper, curcumin, dexmethylphenidate, dicalcium phosphate, docosahexaenoic acid, folic acid, frankincense, glucosamine, gymnema, gymnema extract, iodine, iron, linoleic acid, lipoic acid, piper betle leaf, dolichos bilforus seed extract, lutein, lycopene, magnesium, magnesium stearate, manganese, melatonin, molybdenum, niacin, oleic acid, palmitic acid, panthothenic acid, passion flower, phosphorus, a plant sterol, resvida, selenium, squalene, ginseng, tocopherols, vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin C, vitamin K, zinc, and combinations thereof.

15. The capsule of claim 1 , wherein the first ingredient is a tocotrienol and the second ingredient is selected from vitamin B6, vitamin B 12, or a combination thereof.

16. The capsule of claim 1 , wherein the second ingredient is selected from an oil, a powder, a liquid, a microbead, a beadlet, a granule, a semi-solid, a gel, or a combination thereof.

17. A multi-compartment capsule comprising:

a body;

a diaphragm, having two sidewalls and a bottom, extending into the body and defining a first compartment between an outer surface of the diaphragm and an inner surface of the body; and

a cap mounted to an outer surface of the body and opposed to the diaphragm, and defining a second compartment between an inner surface of the diaphragm and the cap;

wherein the two sidewalls of the diaphragm extend along and contact the inner surface of the body and are aligned with an open end of the body, forming a seal between the diaphragm and the body;

wherein the first compartment is configured to have a volume between 45% and 80% of a total volume of the multi-compartment capsule;

wherein the first compartment contains a first ingredient and the second compartment contains a second ingredient; and

wherein the total volume of the multi-compartment capsule is from about 910 mm 3 to about 950 mm 3 , containing the first compartment and the second compartment therein.