IP Library › Granted Patent US 10,668,125
Granted Patent B2
US 10,668,125 · App. 15/776,609 · Granted Jun 2, 2020

Peptide having highly-shifted accumulation to pancreatic cancer cells and tissues, and use of said peptide

Inventors: Eisaku Kondo (Niigata, JP); Ken Saito (Niigata, JP)
Assignee: Niigata University
A61K38/012A61K38/02A61K45/06A61K47/36A61K47/42A61K49/0043A61K49/0056A61P35/00C07K7/06C07K7/08C12N15/62G01N33/57438A61K9/0019
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Quick Facts
Patent No.
US 10,668,125
App. No.
15/776,609
Granted
Jun 2, 2020
Kind
B2
Abstract

Disclosed is a peptide of the following (a) or (b): (a) a peptide containing an amino acid sequence including a sequence set forth in any one of SEQ ID NOS: 1, 2, 3, and 4; and (b) a peptide containing an amino acid sequence including a sequence having at least 60% identity with a sequence set forth in any one of SEQ ID NOS: 1, 2, 3, and 4, the peptide having highly-shifted accumulation to pancreatic cancer cells and tissues.

Claims (10)

1. A peptide consisting of:

(a) the amino acid sequence of SEQ ID NO: 4; or

(b) an amino acid sequence having at least 90% identity with the amino acid sequence of SEQ ID NO: 4.

2. The peptide according to claim 1 , wherein the peptide comprises L-amino acids.

3. A carrier comprising a peptide of claim 1 ; and a marker or modifier, bonded to the peptide.

4. The carrier according to claim 3 , wherein the marker is one selected from the group consisting of a stable isotope, a radioisotope, and a fluorescent substance.

5. The carrier according to claim 3 , wherein the modifier is one selected from the group consisting of a sugar chain and polyethylene glycol.

6. A pharmaceutical composition comprising:

a peptide of claim 1 ; and

a physiologically active substance.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2025
From: NIIGATA UNIVERSITY
To: KANSAI MEDICAL UNIVERSITY EDUCATIONAL CORPORATION
Reel/Frame 069935/0574 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2018
From: KONDO, EISAKU; SAITO, KEN
To: NIIGATA UNIVERSITY
Reel/Frame 046753/0354 →
Priority Claims (1)
JP 2015-226228 · Nov 19, 2015 · national
Continuity (1)
Related Publication 20180360903A1 · Dec 20, 2018