Veterinary formulations
The present invention relates to various topical veterinary compositions comprising fipronil, an insect growth regulator, and a veterinarily acceptable carrier.
1. A topical formulation consisting of:
(i) 5 to 15% (w/v) fipronil;
(ii) 5 to 15% (w/v) methoprene;
(iii) one or more antioxidants; and
(iv) an organic solvent which is N-methylpyrrolidone.
2. The topical formulation of claim 1 , wherein fipronil is present in a concentration of 8 to 12% (w/v).
3. The topical formulation of claim 1 , wherein methoprene is present in a concentration of 8 to 12% (w/v).
4. The topical formulation of claim 1 , wherein the antioxidant is selected from the group consisting of butylhydroxyanisole, butylhydroxytoluene, ascorbic acid, sodium metabisulphite, propyl gallate and sodium thiosulphate, and mixtures thereof.
5. The topical formulation of claim 4 , wherein the antioxidant is butylhydroxyanisole or butylhydroxytoluene, or a combination thereof.