IP Library Granted Patent US 11,304,925
Granted Patent B1
US 11,304,925 · App. 15/780,579 · Granted Apr 19, 2022

Cannabis composition

Inventors: Harry Karelis (Perth, AU); Mara Gordon (Bodega Bay, CA); Stewart Smith (Bodega Bay, CA); Stewart Washer (Stirling, AU)
Assignee: ZELDA THERAPEUTICS OPERATIONS PTY LTD
A61K31/352A61K31/05A61K45/06A61P35/00
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Quick Facts
Patent No.
US 11,304,925
App. No.
15/780,579
Granted
Apr 19, 2022
Kind
B1
Abstract

The invention relates to a method for treating cancer or a symptom associated with cancer. In particular, the present invention relates to a method for treating cancer or a symptom associated with cancer, comprising administering to a patient in need thereof an effective amount of the pharmaceutical composition comprising a Cannabis extract that comprises Δ 9 -tetrahydrocannabinol (THC) in an amount of from 50% to 99% by weight of the pharmaceutical composition.

Claims (18)

1. A pharmaceutical composition comprising a Cannabis extract and optionally one or more pharmaceutically acceptable carriers, diluents, adjuvants, excipients or any combination thereof, the Cannabis extract comprising a cannabinoid fraction and a terpene fraction, wherein the Cannabis extract comprises:

A:

≥0.3% w/w of the terpene fraction;

≥50% w/w Δ 9 -Tetrahydrocannabinol (THC);

≥0.3% w/w Cannabigerol (CBG); and

≤0.5% w/w Cannabinol (CBN);

wherein the terpene fraction comprises:

ß-caryophyllene in an amount of at least 11% by weight of the terpene fraction,

linalool in an amount of at least 5% by weight of the terpene fraction; and

ß-pinene in an amount of at least 1% by weight of the terpene fraction.

2. The pharmaceutical composition of claim 1 , wherein the Cannabis extract is a Cannabis oil.

3. The pharmaceutical composition of claim 1 , wherein, for composition A, the Cannabis extract comprises Δ 9 -tetrahydrocannabinol (THC) in an amount of from 50% to 99% by weight of the pharmaceutical composition.

4. The pharmaceutical composition of claim 1 , wherein the Cannabis extract comprises one or more additional cannabinoids selected from Δ 9 -Tetrahydrocannabinolic acid (THCA), Δ 9 -Tetrahydrocannabivarin (THCV), and (−)-Cannabidivarin (CBDV).

5. The pharmaceutical composition of claim 1 , wherein the terpene fraction further comprises one or more of ß-myrcene, D-limonene, a nerolidol and α-pinene.

6. The pharmaceutical composition of claim 1 , wherein the terpene fraction further comprises one or more of α-bisabolol, caryophyllene oxide, p-cymene, isopulegol, ocimene, α-terpinene, γ-terpinene, δ-s-carene, guaiol, and terpinolene.

7. The pharmaceutical composition of claim 1 , wherein the pharmaceutically acceptable carrier is sesame oil.

8. The pharmaceutical composition of claim 1 , further comprising an active agent other than the Cannabis extract.

9. The pharmaceutical composition of claim 1 for treating cancer or a symptom associated with cancer.

Assignments (2)
CHANGE OF NAME Recorded Nov 10, 2022
From: ZELDA THERAPEUTICS OPERATIONS PTY LTD
To: ZELIRA THERAPEUTICS OPERATIONS PTY LTD
Reel/Frame 061723/0445 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2019
From: KARELIS, HARRY; GORDON, MARA; SMITH, STEWART; WASHER, STEWART
To: ZELDA THERAPEUTICS OPERATIONS PTY LTD
Reel/Frame 048690/0667 →
Priority Claims (2)
AU 2017901222 · Apr 4, 2017 · national
AU 2017902065 · May 31, 2017 · national
Continuity (1)
Provisional Application 62370299 · Aug 3, 2016
Cited By (1)
US 12,239,628