Thermal modification to treat cardiac electrical disorders and other disorders
Devices and methods are provided for the treatment of pathological conditions including arrhythmias and trauma using temperature modulation via implantable or worn devices. For example, in one example embodiment this document relates to devices and methods for treating atrial or ventricular fibrillation by cooling the epicardium. The devices and methods can also be used to treat other disorders by applying heating and/or cooling to a patient in a number of different manners.
1. A method of treating cardiac arrhythmia of a heart, the method comprising:
deploying a cardiac treatment device onto a tissue surface of the heart, the cardiac treatment device comprising one or more cooling elements;
activating the one or more cooling elements to deliver cooling to the tissue surface of the heart;
detecting, after the activating the one or more cooling elements, that the cardiac arrhythmia still exists;
applying anti-tachycardia pacing to the heart;
detecting, after the applying anti-tachycardia pacing to the heart, that the cardiac arrhythmia still exists; and
applying electroporation to the heart.
2. The method of claim 1 , wherein the cardiac arrhythmia is an atrial arrhythmia, and wherein the tissue surface is an atrial tissue surface.
3. The method of claim 1 , wherein the cardiac arrhythmia is a ventricular arrhythmia, and wherein the tissue surface is a ventricle tissue surface.
4. The method of claim 1 , further comprising:
detecting, after the applying electroporation to the heart, that the cardiac arrhythmia still exists; and
applying one or more low energy shocks to the heart while simultaneously cooling the heart using the cardiac treatment device.
5. The method of claim 4 , further comprising:
detecting, after the applying one or more low energy shocks to the heart, that the cardiac arrhythmia still exists; and
applying one or more standard defibrillation shocks to the heart while simultaneously cooling the heart or nerves of the heart using the cardiac treatment device.