β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N
A compound of the structure: or a pharmaceutically acceptable salt or composition thereof for the treatment of a host infected with or exposed to an HCV virus or other disorders more fully described herein.
1. A pharmaceutical composition comprising an anti-HCV effective amount of a compound of the formula:
in a pharmaceutically acceptable carrier.
2. The pharmaceutical composition of claim 1 , comprising an effective amount of a compound of the formula:
3. The pharmaceutical composition of claim 1 , comprising an effective amount of a compound of the formula:
4. The pharmaceutical composition of claim 1 , in a dosage form.
5. The pharmaceutical composition of claim 4 , in an oral dosage form.
6. The pharmaceutical composition of claim 5 , in a tablet.
7. The pharmaceutical composition of claim 5 , in a capsule.
8. The pharmaceutical composition of claim 2 , in a dosage form.
9. The pharmaceutical composition of claim 8 , in an oral dosage form.
10. The pharmaceutical composition of claim 9 , in a tablet.
11. The pharmaceutical composition of claim 9 , in a capsule.
12. The pharmaceutical composition of claim 3 , in a dosage form.
13. The pharmaceutical composition of claim 12 , in an oral dosage form.
14. The pharmaceutical composition of claim 13 , in a tablet.
15. The pharmaceutical composition of claim 13 , in a capsule.
16. A pharmaceutical composition comprising an anti-HCV effective amount of a compound of the formula:
in a pharmaceutically acceptable carrier.
17. The pharmaceutical composition of claim 16 , comprising an effective amount of a compound of the formula:
18. The pharmaceutical composition of claim 16 , comprising an effective amount of a compound of the formula:
19. The pharmaceutical composition of claim 16 , in a dosage form.
20. The pharmaceutical composition of claim 19 , in an oral dosage form.
21. The pharmaceutical composition of claim 20 , in a tablet.
22. The pharmaceutical composition of claim 20 , in a capsule.
23. The pharmaceutical composition of claim 17 , in a dosage form.
24. The pharmaceutical composition of claim 23 , in an oral dosage form.
25. The pharmaceutical composition of claim 24 , in a tablet.
26. The pharmaceutical composition of claim 24 , in a capsule.
27. The pharmaceutical composition of claim 18 , in a dosage form.
28. The pharmaceutical composition of claim 27 , in an oral dosage form.
29. The pharmaceutical composition of claim 28 , in a tablet.
30. The pharmaceutical composition of claim 28 , in a capsule.