IP Library Granted Patent US 10,668,029
Granted Patent B2
US 10,668,029 · App. 15/789,756 · Granted Jun 2, 2020

Compositions containing non-polar compounds

Inventor: Philip J. Bromley (Fullerton, CA)
Assignee: Virun, Inc.
A61K31/122A23L33/10A23L33/11A23L33/12A23L33/15A61K9/1075A61K31/202A23V2002/00
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Quick Facts
Patent No.
US 10,668,029
App. No.
15/789,756
Granted
Jun 2, 2020
Kind
B2
Abstract

Provided herein are compositions and methods for preparing foods and beverages that contain additives, such as nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.

Claims (24)

1. A liquid nanoemulsion concentrate, comprising:

a non-polar active ingredient;

a tocopherol polyethylene glycol succinate (TPGS) surfactant; and

a polar protic solvent, wherein:

the particles of the concentrate have a size that is less than about 500 nm;

the amount of non-polar active ingredient is between about 5% and about 10%, by weight, of the concentrate;

the amount of TPGS surfactant is between about 18% and about 25%, by weight, of the concentrate;

the amount of polar solvent is between about 60% and about 76%, by weight, of the concentrate; and

the non-polar active ingredient is not TPGS.

2. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient is selected from among any one or more of polyunsaturated fatty acids, Coenzyme Q10 compounds and phytosterols.

3. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient is one or more polyunsaturated fatty acids.

4. The liquid nanoemulsion concentrate of claim 1 , wherein the non-polar active ingredient comprises at least one polyunsaturated fatty acid selected from among omega-3 fatty acids, omega-6 fatty acids, and conjugated fatty acids.

5. The liquid nanoemulsion concentrate of claim 4 , wherein the non-polar active ingredient comprises a polyunsaturated fatty acid selected from among a docosahexaenoic acid (DHA), an eicosapentaenoic acid (EPA), a fish oil, a flaxseed oil, a borage oil, an alpha-linolenic acid (ALA), a gamma-linolenic acid (GLA), a conjugated linoleic acid (CLA), and a saw palmetto extract.

6. The liquid nanoemulsion concentrate of claim 1 , wherein the polar protic solvent is selected from among water, glycerin, propylene glycol, ethylene glycol, tetraethylene glycol, triethylene glycol and trimethylene glycol.

7. The liquid nanoemulsion concentrate of claim 6 , wherein the polar protic solvent is water.

8. The liquid nanoemulsion concentrate of claim 7 , wherein the amount of water is between about 65% and 76%, by weight, of the concentrate.

9. The liquid nanoemulsion concentrate of claim 1 , wherein the TPGS is TPGS-1000.

10. The liquid nanoemulsion concentrate of claim 9 , wherein the polar solvent is water; and the non-polar active ingredient comprises at least one polyunsaturated fatty acid.

11. The liquid nanoemulsion concentrate of claim 1 , further comprising a co-surfactant at an amount sufficient to stabilize the concentrate, compared to the absence of the co-surfactant.

12. The liquid nanoemulsion concentrate of claim 11 , wherein the co-surfactant is a phospholipid that comprises phosphatidylcholine.

13. The liquid nanoemulsion concentrate of claim 1 , further comprising at least one preservative in an amount sufficient to preserve the concentrate, compared to the absence of the preservative.

14. The liquid nanoemulsion concentrate of claim 13 , wherein the at least one preservative comprises benzyl alcohol.

15. The liquid nanoemulsion concentrate of claim 1 , further comprising an emulsion stabilizer in an amount sufficient to stabilize the concentrate, compared to the absence of the emulsion stabilizer.

16. The liquid nanoemulsion concentrate of claim 15 , wherein the emulsion stabilizer comprises a blend of gums.

Assignments (2)
MERGER Recorded Oct 25, 2017
From: VIRUN, INC.
To: VIRUN, INC.
Reel/Frame 043944/0244 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 25, 2017
From: BROMLEY, PHILIP J.
To: VIRUN, INC.
Reel/Frame 043944/0259 →
Continuity (5)
Division 13573440 · Sep 14, 2012
Continuation 12383244 · Mar 20, 2009
Provisional Application 61132424 · Jun 16, 2008
Provisional Application 61070381 · Mar 20, 2008
Related Publication 20180042865A1 · Feb 15, 2018