IP Library Granted Patent US 10,935,645
Granted Patent B2
US 10,935,645 · App. 15/793,969 · Granted Mar 2, 2021

Method and apparatus for low-power ultraportable ultrasound imaging

Inventors: Siddhartha Sikdar (Washington, DC); Parag Chitnis (Fairfax, VA); Nima Akhlaghi (Sterling, VA); Elizabeth Tarbox (Nokesville, VA); Paul Otto (Lorton, VA); Paul Gammell (Exmore, VA)
Assignee: GEORGE MASON UNIVERSITY
G01S7/52025A61B8/5207A61B8/54G01N29/0672G01N29/07G01N29/262G01N29/265G01N29/348G01N29/42G01S15/8913G01S15/8915G01S15/8954G01S15/8977A61B8/4494G01S7/52096
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Quick Facts
Patent No.
US 10,935,645
App. No.
15/793,969
Granted
Mar 2, 2021
Kind
B2
Abstract

Methods, systems, and apparatuses are disclosed for ultrasound imaging comprising Time Delay Spectrometry. A frequency swept signal can be transmitted through a medium, such as human tissue. The signal can be a low-voltage signal (e.g., 0 volts to 5 volts peak-to-peak) transmitted for long duration (e.g., 20 milliseconds) at various frequencies. As the signal propagates through the medium it can be reflected and delayed. A delay associated with the signal the can cause a change in the associated frequencies. The signal can be filtered to retain only frequencies in an audio frequency range. The signal can be beamformed and processed to produce an image.

Claims (50)

1. A method comprising:

transmitting, from a source via a transmit channel of a transducer, a swept frequency signal through a medium;

determining, based on a time delay associated with the swept frequency signal, a plurality of frequencies, wherein the time delay associated with the swept frequency signal is based on the swept frequency signal propagating through the medium;

determining, based on:

one or more components of the swept frequency signal received via a receive channel of the transducer,

a low-pass filter, and

a range,

one or more frequencies associated with the swept frequency signal, wherein the one or more components comprise a sum-frequency component and a difference-frequency component, and wherein the low-pass filter is configured to filter one or more of the sum-frequency component or the difference-frequency component;

and

determining, based on the one or more frequencies and a steering angle, an image.

2. The method of claim 1 , wherein the image is an electrical representation of a region of interest associated with the medium.

3. The method of claim 1 , wherein the medium is a tissue.

4. The method of claim 1 , wherein determining the one or more frequencies associated with the swept frequency signal comprises a Fourier Transformation of at least a portion of the swept frequency signal.

5. The method of claim 1 , wherein the swept frequency signal comprises a voltage of five volts or less.

6. The method of claim 1 , wherein the image is determined in real-time.

7. The method of claim 1 , wherein the transmit channel of the transducer comprises a two-channel transmit element and the receive channel of the transducer comprises a 4-channel receive element.

8. The method of claim 1 , wherein the range comprises frequencies associated with audio frequencies.

9. An apparatus comprising:

one or more processors;

a transducer; and

memory storing processor executable instructions that, when executed by the one or more processors, cause the apparatus to:

transmit, via a transmit channel of the transducer, a swept frequency signal through a medium;

determine, based on a time delay associated with the swept frequency signal, a plurality of frequencies, wherein the time delay associated with the swept frequency signal is based on the swept frequency signal propagating through the medium;

determine, based on:

one or more components of the swept frequency signal received via a receive channel of the transducer,

a low-pass filter, and

a range,

one or more frequencies associated with the swept frequency signal, wherein the one or more components comprise a sum-frequency component and a difference-frequency component, and wherein the low-pass filter is configured to filter one or more of the sum-frequency component or the difference-frequency component;

and

determine, based on the one or more frequencies and a steering angle, an image.

10. The apparatus of claim 9 , wherein the image is an electrical representation of a region of interest associated with the medium.

11. The apparatus of claim 9 , wherein the medium is a tissue.

12. The apparatus of claim 9 , wherein determining the one or more frequencies associated with the swept frequency signal comprises a Fourier Transformation of at least a portion of the swept frequency signal.

13. The apparatus of claim 9 , wherein the swept frequency signal comprises a voltage of five volts or less.

14. The apparatus of claim 9 , wherein the image is determined in real-time.

15. The apparatus of claim 9 , wherein the transmit channel of the transducer comprises a two-channel transmit element and the receive channel of the transducer comprises a 4-channel receive element.

16. The apparatus of claim 9 , wherein the range comprises frequencies associated with audio frequencies.

17. A system comprising

a signal source configured to produce a swept frequency signal;

a dual element transducer configured to:

transmit, via a one or more transmission channels, the swept frequency signal through a medium; and

receive, via a one or more receiving channels, one or more components of the swept frequency signal, wherein the one or more components comprise a sum-frequency component, a difference-frequency component, and a time delay;

one or more mixers configured to output the sum-frequency component and the difference-frequency component;

one or more low pass filters configured to filter the swept frequency signal by filtering one or more of the sum-frequency component or the difference-frequency component; and

a digital signal processor configured:

to process the filtered swept frequency signal; and

generate, based on the processing, an image.

18. The system of claim 17 , wherein the image is an electrical representation of a region of interest associated with the medium.

19. The system of claim 17 , wherein the medium is a tissue.

20. The system of claim 17 , wherein the image is determined in real-time.

Assignments (2)
CONFIRMATORY LICENSE Recorded Nov 2, 2018
From: GEORGE MASON UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 047406/0008 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 23, 2018
From: SIKDAR, SIDDHARTHA; CHITNIS, PARAG; AKHLAGHI, NIMA; OTTO, PAUL; GAMMELL, PAUL; TARBOX, ELIZABETH
To: GEORGE MASON UNIVERSITY
Reel/Frame 044703/0671 →
Continuity (2)
Provisional Application 62412568 · Oct 25, 2016
Related Publication 20180113205A1 · Apr 26, 2018