Blocking IL-9 signaling in conjunction with chemotherapy to treat cancer
This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
1. A method for treating a mammal having colon or breast cancer, wherein said method comprises administering a therapeutically effective amount of an inhibitor of IL-9 signaling alone to said mammal, wherein said inhibitor is an anti-IL-9 antibody, and wherein the progression of said colon or breast cancer or the number of colon or breast cancer cells within said mammal is reduced.
2. The method of claim 1 , wherein said mammal is a human.